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Varying Oxygen Partial Pressure Elicits Blood-Borne Microparticles Expressing Different Cell-Specific Proteins-Toward a Targeted Use of Oxygen?
17 juillet 2022, BALESTRA, Costantino; Arya, Awadhesh; Leveque, Clément; Virgili, Fabio; GERMONPRÉ, Peter; LAMBRECHTS, Kate; Lafere, Pierre; Thom, Stephen,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Oxygen is a powerful trigger for cellular reactions, but there are few comparative investigations assessing the effects over a large range of partial pressures. We investigated a metabolic response to single exposures to either normobaric (10%, 15%, 30%, 100%) or hyperbaric (1.4 ATA, 2.5 ATA) oxygen. Forty-eight healthy subjects (32 males/16 females; age: 43.7 +/- 13.4 years, height: 172.7 +/- 10.07 ...
Ultrasound lung "comets" increase after breath-hold diving
23 octobre 2010, LAMBRECHTS, Kate; GERMONPRÉ, Peter; Charbel, Brian; Cialoni, Danilo; Musimu, Patrick; Sponsiello, Nicola; Marroni, Alessandro; Pastouret, Fredéric; BALESTRA, Costantino,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
The purpose of the study was to analyze the ultrasound lung comets (ULCs) variation, which are a sign of extra-vascular lung water. Forty-two healthy individuals performed breath-hold diving in different conditions: dynamic surface apnea; deep variable-weight apnea and shallow, face immersed without effort (static maximal and non-maximal). The number of ULCs was evaluated by means of an ultrasound ...
The effect of pre-dive ingestion of dark chocolate on endothelial function after a scuba dive
15 mars 2015, THEUNISSEN, Sigrid; BALESTRA, Costantino; BOUTROS, Antoine; De Bels, David; Guerrero, François; GERMONPRÉ, Peter,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Objective: The aim of the study was to observe the effects of dark chocolate on endothelial function after scuba diving.
Methods: Forty-two male scuba divers were divided into two groups: a control (n=21) and a chocolate group (n=21). They performed a 33-metres deep scuba-air dive for 20 minutes in a diving pool (Nemo 33, Brussels). Water temperature was 33⁰C. The chocolate group ingested 30 g ...
The 'normobaric oxygen paradox': does it increase haemoglobin?
14 juin 2012, De Bels, David; THEUNISSEN, Sigrid; Devriendt, Jacques; GERMONPRÉ, Peter; Lafère, Pierre; Valsamis, Joseph; SNOECK, Thyl; Meeus, Philippe; BALESTRA, Costantino,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Background: A novel approach to increasing erythropoietin (EPO) using oxygen (O2) (the 'normobaric oxygen paradox') has been reported in healthy volunteers. We investigated whether the EPO increase is sufficient to induce erythropoiesis by comparing two protocols of O2 administration.
Methods: We compared the effect of daily versus alternate days 100% O2, breathed for 30 minutes, on haemoglobin ...
Static Metabolic Bubbles as Precursors of Vascular Gas Emboli During Divers' Decompression: A Hypothesis Explaining Bubbling Variability
30 juillet 2019, Imbert, Jean Pierre; Egi, Salih Murat; GERMONPRÉ, Peter; BALESTRA, Costantino,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: The risk for decompression sickness (DCS) after hyperbaric exposures (such as SCUBA diving) has been linked to the presence and quantity of vascular gas emboli (VGE) after surfacing from the dive. These VGE can be semi-quantified by ultrasound Doppler and quantified via precordial echocardiography. However, for an identical dive, VGE monitoring of divers shows variations related to ...
Scuba Physiological: Think You Know All About Scuba Medicine? Think again!
01 décembre 2017, Pridmore, Simon; Balestra, Costantino; GERMONPRÉ, Peter,
- HE Bruxelles Brabant
,
- Livre/Ouvrage ou monographie
Livre/Ouvrage ou monographie
"This book makes it easy to understand the latest discoveries in diving research. You will enjoy reading about our current understanding of what happens to our bodies when we dive." JP Imbert: Decompression designer and technical diving pioneer
"As a doctor with a fair history and understanding of diving medicine and diving physiology I found the book interesting. It's the sort of book I would ...
Preconditioning to Reduce Decompression Stress in Scuba Divers
Article scientifique
BACKGROUND: Using ultrasound imaging, vascular gas emboli (VGE) are observed after asymptomatic scuba dives and are considered a key element in the potential development of decompression sickness (DCS). Diving is also accompanied with vascular dysfunction, as measured by flow-mediated dilation (FMD). Previous studies showed significant intersubject variability to VGE for the same diving exposure and ...
Pre-dive Whole-Body Vibration Better Reduces Decompression-Induced Vascular Gas Emboli than Oxygenation or a Combination of Both
30 novembre 2016, BALESTRA, Costantino; THEUNISSEN, Sigrid; Papadopoulou, Virginie; Le Mener, Cédric; GERMONPRÉ, Peter; Guerrero, François; Lafère, Pierre,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Since non-provocative dive profiles are no guarantor of protection against decompression sickness, novel means including pre-dive "preconditioning" interventions, are proposed for its prevention. This study investigated and compared the effect of pre-dive oxygenation, pre-dive whole body vibration or a combination of both on post-dive bubble formation. Methods: Six healthy volunteers performed ...
Physiology of repeated mixed gas 100-m wreck dives using a closed-circuit rebreather: a field bubble study
28 novembre 2021, BALESTRA, Costantino; Guerrero, François; THEUNISSEN, Sigrid; GERMONPRÉ, Peter; Lafère, Pierre,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Data regarding decompression stress after deep closed-circuit rebreather (CCR) dives are scarce. This study aimed to monitor technical divers during a wreck diving expedition and provide an insight in venous gas emboli (VGE) dynamics.
Methods: Diving practices of ten technical divers were observed. They performed a series of three consecutive daily dives around 100 m. VGE counts were ...
Patent Foramen Ovale (PFO), Personality Traits, and Iterative Decompression Sickness. Retrospective Analysis of 209 Cases
20 août 2017, Lafère, Pierre; BALESTRA, Costantino; Caers, Dirk; GERMONPRÉ, Peter,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: There is a need to evaluate the influence of risk factors such as patency of foramen ovale (PFO) or "daredevil" psychological profile on contra-indication policy after a decompression sickness (DCS). Methods: By crossing information obtained from Belgian Hyperbaric Centers, DAN Emergency Hotline, the press, and Internet diving forums, it was possible to be accountable for the majority ...