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Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures
02 août 2023, Leveque, Clément; Mrakic-Sposta, Simona; THEUNISSEN, Sigrid; Germonpré, Peter; LAMBRECHTS, Kate; Vezzoli, Alessandra; Bosco, Gerardo; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Hyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ...
Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia Exposure
15 juin 2023, Leveque, Clément; Mrakic-Sposta, Simona; THEUNISSEN, Sigrid; Germonpré, Peter; LAMBRECHTS, Kate; Vezzoli, Alessandra; Gussoni, Maristella; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
In this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of 10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 females and 8 males, age: 32.2 ± 13.3 years old (mean ± SD), height: 169.1 ± 9.9 cm, and weight: 61.6 ± 16.2 kg) volunteered for the study. Blood samples were taken before, and at 30 min, 2 h, 8 h, 24 h, and 48 h after a 1 ...
Oxidative Stress Response’s Kinetics after 60 Minutes at Different (30% or 100%) Normobaric Hyperoxia Exposures
30 décembre 2022, Leveque, Clément; Mrakic-Sposta, Simona; Lafère, Pierre; Vezzoli, Alessandra; Germonpré, Peter; Beer, Alexandre; Mievis, Stéphane; Virgili, Fabio; LAMBRECHTS, Kate; THEUNISSEN, Sigrid; Guerrero, François; BALESTRA, Costantino,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Oxygen is a powerful trigger for cellular reactions and is used in many pathologies,
including oxidative stress. However, the effects of oxygen over time and at different partial pressures
remain poorly understood. In this study, the metabolic responses of normobaric oxygen intake
for 1 h to mild (30%) and high (100%) inspired fractions were investigated. Fourteen healthy nonsmoking subjects (7 ...
Effects of Acute Hypobaric Hypoxia Exposure on Cardiovascular Function in Unacclimatized Healthy Subjects: A "Rapid Ascent" Hypobaric Chamber Study
28 avril 2022, THEUNISSEN, Sigrid; BALESTRA, Costantino; Bolognési, Sébastien; Borgers, Guy; Vissenaeken, Dirk; Obeid, Georges; Germonpré, Peter; Honoré, Patrick M.; De Bels, David,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Background: This study aimed to observe the effects of a fast acute ascent to simulated high altitudes on cardiovascular function both in the main arteries and in peripheral circulation. Methods: We examined 17 healthy volunteers, between 18 and 50 years old, at sea level, at 3842 m of hypobaric hypoxia and after return to sea level. Cardiac output (CO) was measured with Doppler transthoracic ...
Physiology of repeated mixed gas 100-m wreck dives using a closed-circuit rebreather: a field bubble study
28 novembre 2021, BALESTRA, Costantino; Guerrero, François; THEUNISSEN, Sigrid; GERMONPRÉ, Peter; Lafère, Pierre,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Data regarding decompression stress after deep closed-circuit rebreather (CCR) dives are scarce. This study aimed to monitor technical divers during a wreck diving expedition and provide an insight in venous gas emboli (VGE) dynamics.
Methods: Diving practices of ten technical divers were observed. They performed a series of three consecutive daily dives around 100 m. VGE counts were ...