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Factors influencing the severity of long-term sequelae in fishermen-divers with neurological decompression sickness
31 mars 2020, Blatteau, Jean-Eric; LAMBRECHTS, Kate; Ruffez, Jean,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: Numerous studies have been conducted to identify the factors influencing the short-term prognosis for neurological decompression sickness (DCS). However, the long-term sequelae are rarely assessed. The purpose of this study to investigate the factors likely to influence the long-term prognosis.
Methods: Twenty-seven Vietnamese fishermen-divers who on average 9 (SD 6) years beforehand ...
Simulated air dives induce superoxide, nitric oxide, peroxynitrite, and Ca 2+ alterations in endothelial cells
03 avril 2019, Wang, Qiong; Guerrero, François; LAMBRECHTS, Kate; Theron, Michaël,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Human diving is known to induce endothelial dysfunction. The aim of this study was to decipher the mechanism of ROS production during diving through the measure of mitochondrial calcium concentration, peroxynitrite, NO°, and superoxide towards better understanding of dive-induced endothelial dysfunction. Air diving simulation using bovine arterial endothelial cells (compression rate 101 kPa/min to ...
Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?
11 juillet 2018, LAMBRECHTS, Kate; Demaistre, Sébastien; Blatteau, Jean-Eric; Risso, Jean-Jacques; Vallée, Nicolas,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
In its severest forms, decompression sickness (DCS) may extend systemically and/or induce severe neurological deficits, including paralysis or even death. It seems that the sterile and ischemic inflammatory phenomena are consecutive to the reaction of the bubbles with the organism and that the blood platelet activation plays a determinant role in the development of DCS. According to the hypotheses ...
Venous gas emboli are involved in post-dive macro, but not microvascular dysfunction
21 janvier 2017, LAMBRECHTS, Kate; BALESTRA, Costantino; Theron, Michaël; Henckes, Anne; Galinat, Hubert; Mignant, Fanny; Belhomme, Marc; Pontier, Jean-Michel; Guerrero, François,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Previous studies have shown vascular dysfunction of main conductance arteries and microvessels after diving. We aim to evaluate the impact of bubble formation on vascular function and haemostasis. To achieve this, we used a vibration preconditioning to influence bubble levels without changing any other parameters linked to the dive.
Methods: Twentty-six divers were randomly assigned to ...
Effect of simulated air dive and decompression sickness on the plasma proteome of rats
12 avril 2016, Lautridou, Jacky; Pichereau, Vianney; Artigaud, Sébastien; Buzzacott, Peter; Wang, Qiong; Bernay, Benoit; Driad, Sabrina; Mazur, Aleksandra; LAMBRECHTS, Kate; Theron, Michaël; Guerrero, François,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Decompression sickness (DCS) is a poorly understood systemic disease caused by inadequate desaturation following a reduction in ambient pressure. Although recent studies highlight the importance of circulating factors, the available data are still puzzling. In this study, we aimed to identify proteins and biological pathways involved in the development of DCS in rats.
Experimental design: ...