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    • Early Endothelial Dysfunction in Type 1 Diabetes Is Accompanied by an Impairment of Vascular Smooth Muscle Function: A Meta-AnalysisPeer reviewedOpen access 

      05 mai 2020, Lespagnol, Elodie; Dauchet, Luc; Pawlak-Chaouch, Mehdi; BALESTRA, Costantinoorcid-id; Berthoin, Serge; Feelish, Martin; Roustit, Mathieu; Boissiere, Julien; Fontaine, Pierre; Heyman, Elsa, HE Bruxelles Brabant
      Article scientifique
      Background: A large yet heterogeneous body of literature exists suggesting that endothelial dysfunction appears early in type 1 diabetes, due to hyperglycemia-induced oxidative stress. The latter may also affect vascular smooth muscles (VSM) function, a layer albeit less frequently considered in that pathology. This meta-analysis aims at evaluating the extent, and the contributing risk factors, of ...