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    • Effects of Chemopreventive Natural Compounds on the Accuracy of 8-oxo-7,8-dihydro-2′-deoxyguanosine Translesion SynthesisPeer reviewedClosed access 

      08 juillet 2021, Nachtergael, Amandine; LANTERBECQ, Déborah; SPANOGHE, Martin; Belayew, Alexandra; Duez, Pierre, HE Condorcet
      Article scientifique
      Translesion synthesis is a DNA damage tolerance mechanism that relies on a series of specialized DNA polymerases able to bypass a lesion on a DNA template strand during replication or post-repair synthesis. Specialized translesion synthesis DNA polymerases pursue replication by inserting a base opposite to this lesion, correctly or incorrectly depending on the lesion nature, involved DNA polymerase(s), ...