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Correlation between Patent Foramen Ovale, cerebral “lesions” and neuropsychometric testing in experienced sports divers: does diving damage the brain?
Article scientifique
SCUBA diving exposes divers to decompression sickness (DCS). There has been considerable debate whether divers with a Patent Foramen Ovale of the heart have a higher risk of DCS because of the possible right-to-left shunt of venous decompression bubbles into the arterial circulation. Symptomatic neurological DCS has been shown to cause permanent damage to brain and spinal cord tissue; it has been ...
A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving
07 novembre 2015, BALESTRA, Costantino
; Cimino, Francesco; THEUNISSEN, Sigrid; SNOECK, Thyl; Provyn, Steven; Canali, Raffaella; Bonina, Andrea; Virgili, Fabio,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Nutritional antioxidants have been proposed as an expedient strategy to counter the potentially deleterious effects of scuba diving on endothelial function, flow-mediated dilation (FMD) and heart function. Sixteen volunteers performing a single standard dive (20 min at 33 m) according to US Navy diving procedures were randomly assigned to two groups: one was administered with two doses of 200 mg of ...
Flying after diving: should recommendations be reviewed? In-flight echocardiographic study in bubble-prone and bubble-resistant divers
13 mai 2015, Cialoni, Danilo; Pieri, Massimo; BALESTRA, Costantino
; Marroni, Alessandro,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
INTRODUCTION: Inert gas accumulated after multiple recreational dives can generate tissue supersaturation and bubble formation when ambient pressure decreases. We hypothesized that this could happen even if divers respected the currently recommended 24-hour pre-flight surface interval (PFSI). METHODS: We performed transthoracic echocardiography (TTE) on a group of 56 healthy scuba divers (39 male, ...
Cutis Marmorata skin decompression sickness is a manifestation of brainstem bubble embolization, not of local skin bubbles
10 avril 2015, Germonpré, Peter; BALESTRA, Costantino
; Obeid, Georges; Chers, Dirk,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
"Cutis Marmorata" skin symptoms after diving, most frequently in the form of an itching or painful cutaneous red-bluish discoloration are commonly regarded as a mild form of decompression sickness (DCS), and treated with oxygen inhalation without reverting to hyperbaric recompression treatment. It has been observed that the occurrence of Cutis Marmorata is frequently associated with the presence of ...
Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up
04 avril 2015, Papadopoulou, Virginie; Evgenidis, Sotiris; Eckersley, Robert; Mesimeris, Thodoris; BALESTRA, Costantino
; Kostoglou, Margaritis; Tang, Meng-Xing; Karapantsios, Thodoris,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Vascular gas bubbles are routinely observed after scuba dives using ultrasound imaging, however the precise formation mechanism and site of these bubbles are still debated and growth from decompression in vivo has not been extensively studied, due in part to imaging difficulties. An experimental set-up was developed for optical recording of bubble growth and density on tissue surface area during ...
The effect of pre-dive ingestion of dark chocolate on endothelial function after a scuba dive
15 mars 2015, THEUNISSEN, Sigrid; BALESTRA, Costantino
; BOUTROS, Antoine; De Bels, David; Guerrero, François; GERMONPRÉ, Peter,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Objective: The aim of the study was to observe the effects of dark chocolate on endothelial function after scuba diving.
Methods: Forty-two male scuba divers were divided into two groups: a control (n=21) and a chocolate group (n=21). They performed a 33-metres deep scuba-air dive for 20 minutes in a diving pool (Nemo 33, Brussels). Water temperature was 33⁰C. The chocolate group ingested 30 g ...
Pre-dive Whole-Body Vibration Better Reduces Decompression-Induced Vascular Gas Emboli than Oxygenation or a Combination of Both
17 février 2015, Cavalade, Maxence; Papadopoulou, Virginie; THEUNISSEN, Sigrid; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: The purpose of this study was (1) to further explore the heart rate dynamics and assess a potential cardiovascular risk in response to 4000 m jumps in experienced skydivers; (2) to assess whether there is an impact of such jumps on skydivers' cortical arousal or not, which may impact their decision making processes.
Method: 18 experienced skydivers performed successive jumps from a plane ...
Relationships between plasma lipids, proteins, surface tension and post-dive bubbles
13 février 2015, Schellart, Nico; Rozloznik, Miroslav; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Decompression sickness (DCS) in divers is caused by bubbles of inert gas. When DCS occurs, most bubbles can be found in the venous circulation: venous gas emboli (VGE). Bubbles are thought to be stabilized by low molecular weight surfactant reducing the plasma-air surface tension (γ). Proteins may play a role as well. We studied the interrelations between these substances, γ and VGE, measured before ...
Relationships between plasma lipids, proteins, surface tension and post-dive bubbles
13 février 2015, Schellaert, Nicolas; Rolzoznik, Miroslav; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Decompression sickness (DCS) in divers is caused by bubbles of inert gas. When DCS occurs, most bubbles can be found in the venous circulation: venous gas emboli (VGE). Bubbles are thought to be stabilized by low molecular weight surfactant reducing the plasma-air surface tension (γ). Proteins may play a role as well. We studied the interrelations between these substances, γ and VGE, measured before ...
A ternary model of decompression sickness in rats
01 décembre 2014, Buzzacott, Peter; LAMBRECHTS, Kate; Mazur, Aleksandra; Wang, Qiong; Papadopoulou, Virginie; Theron, Michaël; BALESTRA, Costantino
; Guerrero, François,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Background: Decompression sickness (DCS) in rats is commonly modelled as a binary outcome. The present study aimed to develop a ternary model of predicting probability of DCS in rats, (as no-DCS, survivable-DCS or death), based upon the compression/decompression profile and physiological characteristics of each rat.
Methods: A literature search identified dive profiles with outcomes no-DCS, ...
The "normobaric oxygen paradox": a new tool for the anesthetist?
10 janvier 2014, Rocco, Monica; Ditri, Luciano; De Bels, David; Corazza, Francis; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Hypoxia is the natural trigger for endogenous EPO production but recently the use of intermittent hyperoxia to stimulate EPO has been postulated and this phenomenon has been called the "normobaric oxygen paradox" (NOP). The "NOP" is a mechanism by which oxygen regulates the expression of the Hypoxia Inducible Factor 1 alpha (HIF-1alpha). The HIF-1alpha-depending gene regulation is responsible for ...
Dark chocolate reduces endothelial dysfunction after successive breath-hold dives in cool water
16 septembre 2013, THEUNISSEN, Sigrid; Schumacker, Julie; Guerrero, François; Tillmans, Frauke; BOUTROS, Antoine; Lambrechts, Kate; Mazur, Alexandra; Pieri, Massimo; GERMONPRÉ, Peter; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Objective: The aim of this study is to observe the effects of dark chocolate on endothelial function after a series of successive apnea dives in non-thermoneutral water.
Methods: Twenty breath-hold divers were divided into two groups: a control group (8 males and 2 females) and a chocolate group (9 males and 1 female). The control group was asked to perform a series of dives to 20 m adding up to ...
Effect of a single, open-sea, air scuba dive on human micro- and macrovascular function
15 août 2013, LAMBRECHTS, Kate; Pontier, Jean-Michel; BALESTRA, Costantino
; Mazur, Aleksandra; Wang, Qiong; Buzzacott, Peter; Theron, Michaël; Mansourati, Jacques; Guerrero, François,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Previous studies have shown that bubble formation induced endothelial damage on conduit arteries. We aim to evaluate the effect of diving on microvascular and macrovascular function.
Methods: Nine divers took part in a SCUBA dive at 30 msw (400 kPa), for 30 min of bottom time. Pre- and post-dive, they underwent an assessment of endothelial-dependent (acetylcholine) and endothelial-independent ...
The effect of a passive stretch training protocol on performance during a drop jump in humans
15 juin 2013, Lévénez, Morgan; THEUNISSEN, Sigrid; Bottero, Antoine; SNOECK, Thyl; Bruyère, A; Tinlot, Arnaud; BALESTRA, Costantino
; Provyn, Steven,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Aim: Our study's aim is to show how a five-week stretch training protocol, based on passive stretching, can change muscle performance during a drop jump (stretch shortening cycle).
Methods: This study observes in 8 healthy subjects (four males and four females), the effect of a 5-week passive stretch training protocol on the stretch shortening cycle (SSC) during the performance of a drop jump, ...
Oxidative stress in breath-hold divers after repetitive dives
08 juin 2013, THEUNISSEN, Sigrid; Sponciello, Nicholas; Rozloznik, Miroslav; GERMONPRÉ, Peter; Guerrero, François; Cialoni, Danilo; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: Hyperoxia causes oxidative stress. Breath-hold diving is associated with transient hyperoxia followed by hypoxia and a build-up of carbon dioxide (CO₂), chest-wall compression and significant haemodynamic changes. This study analyses variations in plasma oxidative stress markers after a series of repetitive breath-hold dives.
Methods: Thirteen breath-hold divers were asked to perform ...
Effect of tetrahydrobiopterin and exercise training on endothelium-dependent vasorelaxation in SHR
02 juin 2013, Guerrero, François; Sanéo, Thioub; Goanvec, Christelle; THEUNISSEN, Sigrid; Feray, Annie; BALESTRA, Costantino
; Mansourati, Jacques,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
We examined whether the improvement of impaired NO-dependent vasorelaxation by exercise training could be mediated through a BH4-dependent mechanism. Male spontaneously hypertensive rats (SHR, n = 20) and Wistar-Kyoto rats (WKY, n = 20) were trained (Tr) for 9 weeks on a treadmill and compared to age-matched sedentary animals (Sed). Endothelium-dependent vasorelaxation (EDV) was assessed with ...
The effect of a passive stretch training protocol on performance during a drop jump in humans
30 mars 2013, Levenez, Morgan; THEUNISSEN, Sigrid; Bottero, Antoine; SNOECK, Thyl; Tinlot, Arnaud; BALESTRA, Costantino
; Provyn, Steven,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Our study's aim is to show how a five-week stretch training protocol, based on passive stretching, can change muscle performance during a drop jump (stretch shortening cycle). METHODS: This study observes in 8 healthy subjects (four males and four females), the effect of a 5-week passive stretch training protocol on the stretch shortening cycle (SSC) during the performance of a drop jump, and identify ...
Nitric oxide-related endothelial changes in breath-hold and scuba divers
01 mars 2013, THEUNISSEN, Sigrid; Guerrero, François; Sponciello, Nicholas; Cialoni, Danilo; Pieri, Massimo; GERMONPRÉ, Peter; Obeid, Georges; Tillmans, Frauke; Papadopoulou, Virginie; HEMELRYCK, Walter; Marroni, Alessandro; De Bels, David; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Objective: Scuba and breath-hold divers are compared to investigate whether endothelial response changes are similar despite different exposure(s) to hyperoxia.
Design: 14 divers (nine scuba and five breath-holding) performed either one scuba dive (25m/25 minutes) or successive breath-hold dives at a depth of 20 meters, adding up to 25 minutes of immersion time in a diving pool. Flow-mediated ...
The 'normobaric oxygen paradox': does it increase haemoglobin?
14 juin 2012, De Bels, David; THEUNISSEN, Sigrid; Devriendt, Jacques; GERMONPRÉ, Peter; Lafère, Pierre; Valsamis, Joseph; SNOECK, Thyl; Meeus, Philippe; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Background: A novel approach to increasing erythropoietin (EPO) using oxygen (O2) (the 'normobaric oxygen paradox') has been reported in healthy volunteers. We investigated whether the EPO increase is sufficient to induce erythropoiesis by comparing two protocols of O2 administration.
Methods: We compared the effect of daily versus alternate days 100% O2, breathed for 30 minutes, on haemoglobin ...
Ultrasound lung "comets" increase after breath-hold diving
23 octobre 2010, LAMBRECHTS, Kate; GERMONPRÉ, Peter; Charbel, Brian; Cialoni, Danilo; Musimu, Patrick; Sponsiello, Nicola; Marroni, Alessandro; Pastouret, Fredéric; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
The purpose of the study was to analyze the ultrasound lung comets (ULCs) variation, which are a sign of extra-vascular lung water. Forty-two healthy individuals performed breath-hold diving in different conditions: dynamic surface apnea; deep variable-weight apnea and shallow, face immersed without effort (static maximal and non-maximal). The number of ULCs was evaluated by means of an ultrasound ...
Predive sauna and venous gas bubbles upon decompression from 400 kPa
2008, Blatteau, J.-.É.; Gempp, E.; Mets, T.; GERMONPRÉ, Peter; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
INTRODUCTION: This study investigated the influence of a far infrared-ray dry sauna-induced heat exposure before a simulated dive on bubble formation, and examined the concomitant adjustments in hemodynamic parameters. METHODS: There were 16 divers who were compressed in a hyperbaric chamber to 400 kPa (30 msw) for 25 min and decompressed at 100 kPa x min(-1) with a 4-min stop at 130 kPa. Each diver ...
Pulpal and periodontal temperature rise during KTP laser use as a root planing complement in vitro
2005, Nammour, S.; Rocca, J.-P.; Keiani, K.; BALESTRA, Costantino
; Snoeck, T.; Powell, L.; Van Reck, J.,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
OBJECTIVE: The purpose of this study was to define the optimal irradiation conditions of a KTP laser during root planing treatment. METHODS: The surfaces of 60 single-root human teeth were scaled with conventional instruments before lasing. The pulpal temperature increase was measured by means of one thermocouple placed in the pulp chamber and a second one placed on the root surface at 1 mm from the ...
Evidence for increasing patency of the foramen ovale in divers
2005, GERMONPRÉ, Peter; Hastir, F.; Dendale, P.; Marroni, A.; Nguyen, A.-F.; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
sing a standardized contrast-enhanced transesophageal echocardiographic technique, a group of divers was reexamined for the presence and size of patent foramen ovale (PFO) 7 years after their initial examinations. Unexpected but significant increases in the prevalence and size of PFO were found, suggesting a possible increasing risk for decompression sickness in these divers over time.
Normobaric oxygen can enhance protein captation by the lymphatic system in healthy humans.
janvier 2004, BALESTRA, Costantino
; GERMONPRÉ, Peter; SNOECK, Thyl; Ezquer M; LEDUC, Olivier; Leduc A; Willeput F; Marroni A; Cali Corleo R; Vann R,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
has been advocated for a long time. Several beneficial effects of NBO have been
demonstrated, one of which is the faster elimination of tissue nitrogen bubbles.
During DCS occurrence, a cascade of intravascular reactions has been demonstrated.
These inflammatory reactions occur within minutes of the onset of DCS, and involve the
precipitation of proteins on the gas-bubble interface, causing a ...
The fractal approach as a tool to understand asymptomatic brain hyperintense MRI signals
2004, BALESTRA, Costantino
; Marroni, A.; Farkas, B.; Peetrons, P.; Vanderschueren, F.; Duboc, E.; SNOECK, Thyl; GERMONPRÉ, Peter,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
The prevalence of a Patent Foramen Ovale is described in merely 30% of the asymptomatic population. This patency has been shown to be an increasing risk factor for paradoxical cerebral embolization. Some desaturation or decompression situations in human activities such as scuba diving or altitude flight are prone to provoke embolisations. The association with the presence of a patent Foramen Ovale ...
A deep stop during decompression from 82 fsw (25 m) significantly reduces bubbles and fast tissue gas tensions.
janvier 2004, Marroni A; Bennett PB; Cronje FJ; Cali-Corleo R; GERMONPRÉ, Peter; Pieri M; Bonuccelli C; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
n spite of many modifications to decompression algorithms, the incidence of decompression sickness (DCS) in scuba divers has changed very little. The success of stage, compared to linear ascents, is well described yet theoretical changes in decompression ratios have diminished the importance of fast tissue gas tensions as critical for bubble generation. The most serious signs and symptoms of DCS ...
Erythropoietin production can be enhanced by normobaric oxygen breathing in healthy humans
2004, BALESTRA, Costantino
; GERMONPRÉ, Peter; Poortmans, J.; Marroni, A.; Schiettecatte, J.; Collard, J.-F.; SNOECK, Thyl,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Erythropoietin (EPO) induces red blood cell production by activating red bone marrow
progenitor cells, and is used therapeutically in chronic anemia. It is also used as an unauthorized
adjunct to increase the oxygen transport capacity in the blood of athletes. Renal tissue hypoxia is
the only widely accepted trigger for EPO production (1-3), even if new oxygen-sensitive sites
have been recently ...
Scuba diving can induce stress of the temporomandibular joint leading to headache [1]
2004, BALESTRA, Costantino
; GERMONPRÉ, Peter; Marroni, A.; SNOECK, Thyl,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
In ordinary recreational scuba diving, many anatomical parts can be involved in disorders of cranial regions: ears and eyes are involved but also sinuses. Dental problems are generally involved in barotraumas because of bad dental fillings or other matters of interest to the general dental practitioner.1 Very few papers have looked at the articular and periarticular problems of the temporomandibular
joint ...
Reflex regulation during sustained and intermittent submaximal contractions in humans
2002, Duchateau, J.; BALESTRA, Costantino
; Carpentier, A.; Hainaut, K.,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
To investigate whether the intensity and duration of a sustained contraction influences reflex regulation, we compared sustained fatiguing contractions at 25 % and 50 % of maximal voluntary contraction (MVC) force in the human abductor pollicis brevis (APB) muscle. Because the activation of motoneurones during fatigue may be reflexively controlled by the metabolic status of the muscle, we also ...
Patent foramen ovale and decompression sickness in sports divers.
mai 1998, GERMONPRÉ, Peter; Dendale P; Unger P; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Patency of the foramen ovale (PFO) may be a cause of unexplained decompression sickness (DCS) in sports divers. To assess the relationship between PFO and DCS, a case-control study was undertaken in a population of Belgian sports divers. Thirty-seven divers who suffered from neurological DCS were compared with matched control divers who never had DCS. All divers were investigated with transesophageal ...
Intrathoracic pressure changes after Valsalva strain and other maneuvers: Implications for divers with patent foramen ovale
1998, BALESTRA, Costantino
; GERMONPRÉ, Peter; Marroni, A.,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Scuba divers with patent foramen ovale (PFO) may be at risk for paradoxical nitrogen gas emboli when performing maneuvers that cause a rebound blood loading to the right atrium. We measured the rise and fall in intrathoracic pressure (ITP) during various maneuvers in 15 divers. The tests were standard isometric exercises (control), forceful coughing, knee bend (with and without respiration blocked), ...
Intrathoracic pressure changes after Valsalva strain and other maneuvers: implications for divers with patent foramen ovale.
janvier 1998, GERMONPRÉ, Peter; Marroni A; BALESTRA, Costantino
,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Scuba divers with patent foramen ovale (PFO) may be at risk for paradoxical nitrogen gas emboli when performing maneuvers that cause a rebound blood loading to the right atrium. We measured the rise and fall in intrathoracic pressure (ITP) during various maneuvers in 15 divers. The tests were standard isometric exercises (control), forceful coughing, knee bend (with and without respiration blocked), ...
Effects of fatigue on the stretch reflex in a human muscle
Article scientifique
The effects of fatigue on the electromyographic (EMG) reflex activities were compared during sustained voluntary contractions and contractions evoked by electrical stimulation (30 Hz) in the human first dorsal interosseus (FDI). Short latency (SL), medium latency (ML) and long latency (LL) reflex responses to a ramp-and-hold stretch of the muscle were recorded and analysed in 27 healthy subjects of ...