| dc.rights.license | CC0 | en_US |
| dc.contributor.author | DUBUSON, Macha | |
| dc.contributor.other | Noël, Xavier | |
| dc.contributor.other | Campanella, Salvatore | |
| dc.date.accessioned | 2023-09-12T14:35:45Z | |
| dc.date.available | 2023-09-12T14:35:45Z | |
| dc.date.issued | 2023-04-01 | |
| dc.identifier.uri | https://luck.synhera.be/handle/123456789/2021 | |
| dc.description.abstract | Many societies report a high number of people suffering from behavioral or
substance-related addictions, such as gambling or alcohol. Despite psychotherapy, social support,
withdrawal, or even medication, it is recognized throughout the world that recovering from an
addiction is particularly challenging. Understanding the neurocognitive mechanisms triggering
addictive disorders is therefore particularly relevant to optimizing addiction treatment. In the present
study, we investigated whether or not patients suffering from gambling or alcohol use disorders are
efficient at inhibiting their responses when their attention is attracted by a neutral, rewarding, or
cueing context related to their own addiction (alcohol vs. gambling). Such behavioral and neural
evidence may help clinicians to implement novel targeted intervention more suited to the individual
needs of these patients | en_US |
| dc.description.sponsorship | None | en_US |
| dc.description.tableofcontents | Inhibitory and rewarding processes that mediate attentional biases to
addiction-related cues may slightly differ between patients suffering from alcohol use (AUD) or
gambling (GD) disorder. (2) Methods: 23 AUD inpatients, 19 GD patients, and 22 healthy controls
performed four separate Go/NoGo tasks, in, respectively, an alcohol, gambling, food, and neutral
long-lasting cueing context during the recording of event-related potentials (ERPs). (3) Results: AUD
patients showed a poorer inhibitory performance than controls (slower response latencies, lower N2d,
and delayed P3d components). In addition, AUD patients showed a preserved inhibitory performance
in the alcohol-related context (but a more disrupted one in the food-related context), while GD patients
showed a specific inhibitory deficit in the game-related context, both indexed by N2d amplitude
modulations. (4) Conclusions: Despite sharing common addiction-related mechanisms, AUD and
GD patients showed different patterns of response to (non-)rewarding cues that should be taken into
account in the therapeutic context | en_US |
| dc.language.iso | EN | en_US |
| dc.publisher | biology | en_US |
| dc.publisher | MDPI | en_US |
| dc.relation.ispartof | biology | en_US |
| dc.relation.isreferencedby | https://www.mdpi.com/2079-7737/12/5/643 | en_US |
| dc.rights.uri | unk | en_US |
| dc.subject | Alcohol Use Disorder | en_US |
| dc.title | A Comparative Event-Related Potentials Study between Alcohol Use Disorder, Gambling Disorder and Healthy Control Subjects through a Contextual Go/NoGo Task | en_US |
| dc.type | Article scientifique | en_US |
| synhera.classification | Sciences de la santé humaine | en_US |
| synhera.institution | HE de la Province de Namur | en_US |
| synhera.otherinstitution | Macha Dubuson | en_US |
| synhera.cost.total | unk | en_US |
| synhera.cost.apc | unk | en_US |
| synhera.cost.comp | unk | en_US |
| synhera.cost.acccomp | unk | en_US |
| dc.description.version | Oui | en_US |
| dc.rights.holder | unk | en_US |
