• Age, weight and decompression sickness in ratsPeer reviewedClosed access 

      16 mars 2016, Buzzacott, Peter; Theron, Michaël; Mazur, Aleksandra; Wang, Qiong; LAMBRECHTS, Kate; Eftedal, Ingrid; Berenji, Simin, HE Bruxelles Brabant
      Article scientifique
      Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference ...
    • Effect of simulated air dive and decompression sickness on the plasma proteome of ratsPeer reviewedClosed access 

      12 avril 2016, Lautridou, Jacky; Pichereau, Vianney; Artigaud, Sébastien; Buzzacott, Peter; Wang, Qiong; Bernay, Benoit; Driad, Sabrina; Mazur, Aleksandra; LAMBRECHTS, Kate; Theron, Michaël; Guerrero, François, HE Bruxelles Brabant
      Article scientifique
      Purpose: Decompression sickness (DCS) is a poorly understood systemic disease caused by inadequate desaturation following a reduction in ambient pressure. Although recent studies highlight the importance of circulating factors, the available data are still puzzling. In this study, we aimed to identify proteins and biological pathways involved in the development of DCS in rats. Experimental design: ...
    • Elevations of Extracellular Vesicles and Inflammatory Biomarkers in Closed Circuit SCUBA DiversPeer reviewedOpen access 

      22 mars 2023, Arya, Awadhesh; BALESTRA, Costantino; Bhopale, Veena; Tominen, Laura; Raisanen-Sokolowski, Anne; Dugrenot, Emmanuel; Thom, Stephen, HE Bruxelles Brabant
      Article scientifique
      Blood-borne extracellular vesicles and inflammatory mediators were evaluated in divers using a closed circuit rebreathing apparatus and custom-mixed gases to diminish some diving risks. "Deep" divers (n = 8) dove once to mean (+/-SD) 102.5 +/- 1.2 m of sea water (msw) for 167.3 +/- 11.5 min. "Shallow" divers (n = 6) dove 3 times on day 1, and then repetitively over 7 days to 16.4 +/- 3.7 msw, for ...
    • Endothelial function may be enhanced in the cutaneous microcirculation after a single air divePeer reviewedClosed access 

      30 septembre 2020, Guerrero, François; LAMBRECHTS, Kate; Wang, Qiong; Mazur, Aleksandra; Marroni, Alessandro, HE Bruxelles Brabant
      Article scientifique
      Introduction: The effects of scuba diving on the vessel wall have been studied mainly at the level of large conduit arteries. Data regarding the microcirculation are scarce and indicate that these two vascular beds are affected differently by diving. Methods: We assessed the changes in cutaneous microcirculation before an air scuba dive, then 30 min and 24 h after surfacing. Endothelium-dependent ...
    • Fluoxetine stimulates anti-inflammatory IL-10 cytokine production and attenuates sensory deficits in a rat model of decompression sicknessPeer reviewedOpen access 

      22 octobre 2015, Blatteau, Jean-Eric; De Maistre, Sébastien; LAMBRECHTS, Kate; Abraini, Jacques; Risso, Jean-Jacques; Vallée, Nicolas, HE Bruxelles Brabant
      Article scientifique
      Despite "gold standard" hyperbaric oxygen treatment, 30% of patients suffering from neurological decompression sickness still exhibit incomplete recovery, including sensory impairments. Fluoxetine, a well-known antidepressant, is recognized as having anti-inflammatory effects in the setting of cerebral ischemia. In this study, we focused on the assessment of sensory neurological deficits and measurement ...
    • Full-Face Mask Use during SCUBA Diving Counters Related Oxidative Stress and Endothelial DysfunctionPeer reviewedOpen access 

      15 janvier 2022, Levenez, Morgan; LAMBRECHTS, Kate; Mrakic-Sposta, Simona; Vezzoli, Alessandra; Germonpré, Peter; Pique, Hadrien; Virgili, Fabi; Bosco, Gerardo; Lafere, Pierre; BALESTRA, Costantino, HE Bruxelles Brabant
      Article scientifique
      Impaired flow mediated dilation (FMD), an index of vascular stress, is known after SCUBA diving. This is related to a dysfunction of nitric oxide (NO) availability and a disturbance of the redox status, possibly induced by hyperoxic/hyperbaric gas breathing. SCUBA diving is usually performed with a mask only covering "half face" (HF) and therefore forcing oral breathing. Nasal NO production is ...
    • Heart Rate Variability During a Standard Dive: A Role for Inspired Oxygen Pressure?Peer reviewedOpen access 

      13 août 2021, Lafère, Pierre; LAMBRECHTS, Kate; GERMONPRÉ, Peter; BALESTRA, Ambre; Germonpré, Faye-Lisa; Marroni, Alessandro; Cialoni, Danilo; Bosco, Gerardo; BALESTRA, Costantino, HE Bruxelles Brabant
      Article scientifique
      Introduction: Heart rate variability (HRV) during underwater diving has been infrequently investigated because of environment limitations and technical challenges. This study aims to analyze HRV changes while diving at variable hyperoxia when using open circuit (OC) air diving apparatus or at constant hyperoxia using a closed-circuit rebreather (CCR). We used HRV analysis in time and frequency domain ...
    • Hydration status during commercial saturation diving measured by bioimpedance and urine specific gravityPeer reviewedOpen access 

      29 septembre 2022, Werke, Stian Lande; Landswerk, Halvor Dagsson; Lautridou, Jacky; Imbert, Jean-Pierre; BALESTRA, Costantino; Eftedal, Ingrid, HE Bruxelles Brabant
      Article scientifique
      Excessive fluid loss triggered by hyperbaric pressure, water immersion and hot water suits causes saturation divers to be at risk of dehydration. Dehydration is associated with reductions in mental and physical performance, resulting in less effective work and an increased risk of work-related accidents. In this study we examined the hydration status of 11 male divers over 19 days of a commercial ...
    • Investigating critical flicker fusion frequency for monitoring gas narcosis in diversPeer reviewedOpen access 

      17 décembre 2020, Vrijdag, Xavier; Van Waart, Hanna; Sleigh, Jaimie; BALESTRA, Costantino; Mitchell, Simon, HE Bruxelles Brabant
      Article scientifique
      INTRODUCTION: Critical flicker fusion frequency (CFFF) has been used in various studies to measure the cognitive effects of gas mixtures at depth, sometimes with conflicting or apparently paradoxical results. This study aimed to evaluate a novel automatic CFFF method and investigate whether CFFF can be used to monitor gas-induced narcosis in divers. METHODS: Three hyperbaric chamber experiments were ...
    • Pulmonary Effects of One Week of Repeated Recreational Closed-Circuit Rebreather Dives in Cold WaterPeer reviewedOpen access 

      28 décembre 2022, Gouin, Emmanuel; BALESTRA, Costantino; Orsat, Jeremy; Dugrenot, Emmanuel; L'Her, Erwan, HE Bruxelles Brabant
      Article scientifique
      Background and Objectives: The use of closed-circuit rebreathers (CCRs) in recreational diving is gaining interest. However, data regarding its physiological effects are still scarce. Immersion, cold water, hyperoxia, exercise or the equipment itself could challenge the cardiopulmonary system. The purpose of this study was to examine the impact of CCR diving on lung function and autonomous cardiac ...