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    • Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia ExposuresPeer reviewedOpen access 

      02 août 2023, Leveque, Clément; Mrakic-Sposta, Simona; THEUNISSEN, Sigrid; Germonpré, Peter; LAMBRECHTS, Kate; Vezzoli, Alessandra; Bosco, Gerardo; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
      Article scientifique
      Hyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ...

    • Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia ExposurePeer reviewedOpen access 

      15 juin 2023, Leveque, Clément; Mrakic-Sposta, Simona; THEUNISSEN, Sigrid; Germonpré, Peter; LAMBRECHTS, Kate; Vezzoli, Alessandra; Gussoni, Maristella; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
      Article scientifique
      In this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of 10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 females and 8 males, age: 32.2 ± 13.3 years old (mean ± SD), height: 169.1 ± 9.9 cm, and weight: 61.6 ± 16.2 kg) volunteered for the study. Blood samples were taken before, and at 30 min, 2 h, 8 h, 24 h, and 48 h after a 1 ...

    • Oxidative Stress Response’s Kinetics after 60 Minutes at Different (30% or 100%) Normobaric Hyperoxia ExposuresPeer reviewedOpen access 

      30 décembre 2022, Leveque, Clément; Mrakic-Sposta, Simona; Lafère, Pierre; Vezzoli, Alessandra; Germonpré, Peter; Beer, Alexandre; Mievis, Stéphane; Virgili, Fabio; LAMBRECHTS, Kate; THEUNISSEN, Sigrid; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
      Article scientifique
      Oxygen is a powerful trigger for cellular reactions and is used in many pathologies, including oxidative stress. However, the effects of oxygen over time and at different partial pressures remain poorly understood. In this study, the metabolic responses of normobaric oxygen intake for 1 h to mild (30%) and high (100%) inspired fractions were investigated. Fourteen healthy nonsmoking subjects (7 ...