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Increasing Oxygen Partial Pressures Induce a Distinct Transcriptional Response in Human PBMC: A Pilot Study on the “Normobaric Oxygen Paradox”![Peer reviewed Peer reviewed](/themes/Mirage2//images/peer_review.svg)
05 janvier 2021,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
The term "normobaric oxygen paradox" (NOP), describes the response to the return to normoxia after a hyperoxic event, sensed by tissues as oxygen shortage, and resulting in up-regulation of the Hypoxia-inducible factor 1alpha (HIF-1alpha) transcription factor activity. The molecular characteristics of this response have not been yet fully characterized. Herein, we report the activation time trend ...
Investigating critical flicker fusion frequency for monitoring gas narcosis in divers![Peer reviewed Peer reviewed](/themes/Mirage2//images/peer_review.svg)
17 décembre 2020,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
INTRODUCTION: Critical flicker fusion frequency (CFFF) has been used in various studies to measure the cognitive effects of gas mixtures at depth, sometimes with conflicting or apparently paradoxical results. This study aimed to evaluate a novel automatic CFFF method and investigate whether CFFF can be used to monitor gas-induced narcosis in divers. METHODS: Three hyperbaric chamber experiments were ...