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Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia Exposure
15 juin 2023,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
In this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of 10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 females and 8 males, age: 32.2 ± 13.3 years old (mean ± SD), height: 169.1 ± 9.9 cm, and weight: 61.6 ± 16.2 kg) volunteered for the study. Blood samples were taken before, and at 30 min, 2 h, 8 h, 24 h, and 48 h after a 1 ...
Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures
02 août 2023,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Hyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ...
Varying Oxygen Partial Pressure Elicits Blood-Borne Microparticles Expressing Different Cell-Specific Proteins-Toward a Targeted Use of Oxygen?
17 juillet 2022,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Oxygen is a powerful trigger for cellular reactions, but there are few comparative investigations assessing the effects over a large range of partial pressures. We investigated a metabolic response to single exposures to either normobaric (10%, 15%, 30%, 100%) or hyperbaric (1.4 ATA, 2.5 ATA) oxygen. Forty-eight healthy subjects (32 males/16 females; age: 43.7 +/- 13.4 years, height: 172.7 +/- 10.07 ...
Full-Face Mask Use during SCUBA Diving Counters Related Oxidative Stress and Endothelial Dysfunction
15 janvier 2022,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Impaired flow mediated dilation (FMD), an index of vascular stress, is known after SCUBA diving. This is related to a dysfunction of nitric oxide (NO) availability and a disturbance of the redox status, possibly induced by hyperoxic/hyperbaric gas breathing. SCUBA diving is usually performed with a mask only covering "half face" (HF) and therefore forcing oral breathing. Nasal NO production is ...
Mini Trampoline, a New and Promising Way of SCUBA Diving Preconditioning to Reduce Vascular Gas Emboli?
29 avril 2022,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Background: Despite evolution in decompression algorithms, decompression illness is still an issue nowadays. Reducing vascular gas emboli (VGE) production or preserving endothelial function by other means such as diving preconditioning is of great interest. Several methods have been tried, either mechanical, cardiovascular, desaturation aimed or biochemical, with encouraging results. In this study, ...
Heart Rate Variability During a Standard Dive: A Role for Inspired Oxygen Pressure?
13 août 2021,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: Heart rate variability (HRV) during underwater diving has been infrequently investigated because of environment limitations and technical challenges. This study aims to analyze HRV changes while diving at variable hyperoxia when using open circuit (OC) air diving apparatus or at constant hyperoxia using a closed-circuit rebreather (CCR). We used HRV analysis in time and frequency domain ...
Oxidative Stress Response’s Kinetics after 60 Minutes at Different (30% or 100%) Normobaric Hyperoxia Exposures
30 décembre 2022,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Oxygen is a powerful trigger for cellular reactions and is used in many pathologies,
including oxidative stress. However, the effects of oxygen over time and at different partial pressures
remain poorly understood. In this study, the metabolic responses of normobaric oxygen intake
for 1 h to mild (30%) and high (100%) inspired fractions were investigated. Fourteen healthy nonsmoking subjects (7 ...
Heart Rate Variability During a Standard Dive: A Role for Inspired Oxygen Pressure?
13 août 2021,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: Heart rate variability (HRV) during underwater diving has been infrequently investigated because of environment limitations and technical challenges. This study aims to analyze HRV changes while diving at variable hyperoxia when using open circuit (OC) air diving apparatus or at constant hyperoxia using a closed-circuit rebreather (CCR). We used HRV analysis in time and frequency domain ...
Fluoxetine stimulates anti-inflammatory IL-10 cytokine production and attenuates sensory deficits in a rat model of decompression sickness
22 octobre 2015,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Despite "gold standard" hyperbaric oxygen treatment, 30% of patients suffering from neurological decompression sickness still exhibit incomplete recovery, including sensory impairments. Fluoxetine, a well-known antidepressant, is recognized as having anti-inflammatory effects in the setting of cerebral ischemia. In this study, we focused on the assessment of sensory neurological deficits and measurement ...
Age, weight and decompression sickness in rats
16 mars 2016,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Objective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference ...