HE2B - HE: Recent submissions
Voici les éléments 61-80 de 143
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The "normobaric oxygen paradox": a new tool for the anesthetist?
10 janvier 2014, Rocco, Monica; Ditri, Luciano; De Bels, David; Corazza, Francis; BALESTRA, Costantino
, HE Bruxelles Brabant
Article scientifiqueHypoxia is the natural trigger for endogenous EPO production but recently the use of intermittent hyperoxia to stimulate EPO has been postulated and this phenomenon has been called the "normobaric oxygen paradox" (NOP). The "NOP" is a mechanism by which oxygen regulates the expression of the Hypoxia Inducible Factor 1 alpha (HIF-1alpha). The HIF-1alpha-depending gene regulation is responsible for ... -
Fluoxetine stimulates anti-inflammatory IL-10 cytokine production and attenuates sensory deficits in a rat model of decompression sickness
22 octobre 2015, HE Bruxelles BrabantArticle scientifiqueDespite "gold standard" hyperbaric oxygen treatment, 30% of patients suffering from neurological decompression sickness still exhibit incomplete recovery, including sensory impairments. Fluoxetine, a well-known antidepressant, is recognized as having anti-inflammatory effects in the setting of cerebral ischemia. In this study, we focused on the assessment of sensory neurological deficits and measurement ... -
Age, weight and decompression sickness in rats
16 mars 2016, HE Bruxelles BrabantArticle scientifiqueObjective: The aim of this study was to determine if, after controlling for weight, age is associated with decompression sickness (DCS) in rats. Methods: Following compression-decompression, male rats aged 11 weeks were observed for DCS. After two weeks recovery, surviving rats were re-dived using the same compression-decompression profile. Results: In this experiment, there was a clear difference ... -
Colonic Fermentation Promotes Decompression sickness in Rats
08 février 2016, HE Bruxelles BrabantArticle scientifiqueMassive bubble formation after diving can lead to decompression sickness (DCS). During dives with hydrogen as a diluent for oxygen, decreasing the body's H2 burden by inoculating hydrogen-metabolizing microbes into the gut reduces the risk of DCS. So we set out to investigate if colonic fermentation leading to endogenous hydrogen production promotes DCS in fasting rats. Four hours before an experimental ... -
Effect of simulated air dive and decompression sickness on the plasma proteome of rats
12 avril 2016, HE Bruxelles BrabantArticle scientifiquePurpose: Decompression sickness (DCS) is a poorly understood systemic disease caused by inadequate desaturation following a reduction in ambient pressure. Although recent studies highlight the importance of circulating factors, the available data are still puzzling. In this study, we aimed to identify proteins and biological pathways involved in the development of DCS in rats. Experimental design: ... -
Effect of oxygen-breathing during a decompression-stop on bubble-induced platelet activation after an open-sea air dive: oxygen-stop decompression
29 septembre 2013, HE Bruxelles BrabantArticle scientifiquePurpose: We highlighted a relationship between decompression-induced bubble formation and platelet micro-particle (PMP) release after a scuba air-dive. It is known that decompression protocol using oxygen-stop accelerates the washout of nitrogen loaded in tissues. The aim was to study the effect of oxygen deco-stop on bubble formation and cell-derived MP release. Methods: Healthy experienced ... -
Effect of decompression-induced bubble formation on highly trained divers microvascular function
07 novembre 2013, HE Bruxelles BrabantArticle scientifiqueWe previously showed microvascular alteration of both endothelium-dependent and -independent reactivity after a single SCUBA dive. We aimed to study mechanisms involved in this postdive vascular dysfunction. Ten divers each completed three protocols: (1) a SCUBA dive at 400 kPa for 30 min; (2) a 41-min duration of seawater surface head immersed finning exercise to determine the effect of immersion ... -
Effect of splenectomy on platelet activation and decompression sickness outcome in a rat model of decompression
01 septembre 2014, HE Bruxelles BrabantArticle scientifiqueIntroduction: Splenic platelets have been recognized to have a greater prothrombotic potential than others platelets. We studied whether platelets released by splenic contraction could influence the severity and outcome of decompression sickness (DCS) and bubble-induced platelet activation. Methods: Sixteen, male Sprague-Dawley rats were randomly assigned to either a control or a splenectomized ... -
Mechanism of action of antiplatelet drugs on decompression sickness in rats: a protective effect of anti-GPIIbIIIa therapy
15 mai 2015, HE Bruxelles BrabantArticle scientifiqueLiterature highlights the involvement of disseminated thrombosis in the pathophysiology of decompression sickness (DCS). We examined the effect of several antithrombotic treatments targeting various pathways on DCS outcome: acetyl salicylate, prasugrel, abciximab, and enoxaparin. Rats were randomly assigned to six groups. Groups 1 and 2 were a control nondiving group (C; n = 10) and a control diving ... -
Flying after diving: should recommendations be reviewed? In-flight echocardiographic study in bubble-prone and bubble-resistant divers
13 mai 2015, Cialoni, Danilo; Pieri, Massimo; BALESTRA, Costantino; Marroni, Alessandro, HE Bruxelles Brabant
Article scientifiqueINTRODUCTION: Inert gas accumulated after multiple recreational dives can generate tissue supersaturation and bubble formation when ambient pressure decreases. We hypothesized that this could happen even if divers respected the currently recommended 24-hour pre-flight surface interval (PFSI). METHODS: We performed transthoracic echocardiography (TTE) on a group of 56 healthy scuba divers (39 male, ... -
Cutis Marmorata skin decompression sickness is a manifestation of brainstem bubble embolization, not of local skin bubbles
10 avril 2015, Germonpré, Peter; BALESTRA, Costantino; Obeid, Georges; Chers, Dirk, HE Bruxelles Brabant
Article scientifique"Cutis Marmorata" skin symptoms after diving, most frequently in the form of an itching or painful cutaneous red-bluish discoloration are commonly regarded as a mild form of decompression sickness (DCS), and treated with oxygen inhalation without reverting to hyperbaric recompression treatment. It has been observed that the occurrence of Cutis Marmorata is frequently associated with the presence of ... -
Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up
04 avril 2015, Papadopoulou, Virginie; Evgenidis, Sotiris; Eckersley, Robert; Mesimeris, Thodoris; BALESTRA, Costantino; Kostoglou, Margaritis; Tang, Meng-Xing; Karapantsios, Thodoris, HE Bruxelles Brabant
Article scientifiqueVascular gas bubbles are routinely observed after scuba dives using ultrasound imaging, however the precise formation mechanism and site of these bubbles are still debated and growth from decompression in vivo has not been extensively studied, due in part to imaging difficulties. An experimental set-up was developed for optical recording of bubble growth and density on tissue surface area during ... -
Qu'est-ce qui va changer? - Capitre dans Coeur et Plongée
Livre/Ouvrage ou monographieLe monde sous-marin est devenu accessible au plus grand nombre. Les méthodes de plongée se sont diversifiées, la population de plongeurs aussi... Mais la plongée demeure une activité à risques. Les pathologies cardiaques peuvent faire courir des dangers importants, non seulement au plongeur, mais aussi à tous ceux impliqués en cas d'assistance. Or, les données concernant les décès en plongée mettent ... -
Influence of decompression sickness on vasocontraction of isolated rat vessels
18 février 2015, HE Bruxelles BrabantArticle scientifiqueStudies conducted in divers indicate that endothelium function is impaired following a dive even without decompression sickness (DCS). Our previous experiment conducted on rat isolated vessels showed no differences in endothelium-dependent vasodilation after a simulated dive even in the presence of DCS, while contractile response to phenylephrine was progressively impaired with increased decompression ... -
Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the "spadin" Antidepressant
16 février 2016, HE Bruxelles BrabantArticle scientifiqueIn mice, disseminated coagulation, inflammation, and ischemia induce neurological damage that can lead to death. These symptoms result from circulating bubbles generated by a pathogenic decompression. Acute fluoxetine treatment or the presence of the TREK-1 potassium channel increases the survival rate when mice are subjected to an experimental dive/decompression protocol. This is a paradox because ... -
L' enseignement du FLE à travers les applications en ligne: une didactique novatrice?
01 décembre 2017, HE Bruxelles BrabantArticle scientifiqueExpérimentation de quelques plateformes, applications ou autres sites en ligne permettant l'acquisition ou le perfectionnement de la langue française. Critique de leur configuration, de leur formulation et de leur résolution. -
Apprenant allophone et système scolaire belge : un doute permanent
01 septembre 2015, HE Bruxelles BrabantArticle scientifiqueLes autrices interrogent la place de l'enseignement du FLES dans le système éducatif belge. -
De Handji aux Ténèbres de Robert Poulet: une invitation à l'onirisme réaliste
25 mai 2015, HE Bruxelles BrabantArticle scientifiqueQuelles sont les frontières entre le fantastique dit "classique" et les "réalités fantastiques" théorisées par Hellens? Robert Poulet ne serait-il pas le meilleur disciple d'Hellens en permettant aux lettres belges d'entrer dans une troisième sphère de l'évolution du courant fantastique, celle du Réalisme magique? -
De Bruges-la-Morte de G. Rodenbach aux Ténèbres de R. Poulet: une initiation du lecteur à une nouvelle lecture romanesque
07 novembre 2012, HE Bruxelles BrabantArticle scientifiquePublication parue dans le cadre des journées des jeunes chercheurs de l'Université de Strasbourg. Cette publication entend mettre en avant le jeu particulier d'effacement du narrateur dans deux oeuvres belges majeures. -
Au royaume de Wells, Lear aurait-il pu être roi?
17 juillet 2018, HE Bruxelles BrabantArticle scientifiqueL'oeuvre de Shakespeare, "Le Roi Lear" a-t-il connu des réécritures modernes et contemporaines? A travers cet article, l'autrice démontre que la nouvelle de H.G. Wells, "Le Pays des Aveugles" est une réécriture de King Lear dont les embranchements sont semblables aux strates ou au rhizomes deleuziens.