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Diving physiopathology: the end of certainties? Food for thought
27 juin 2019, HE Bruxelles BrabantArticle scientifiqueOur understanding of decompression physiopathology has slowly improved during this last decade and some uncertainties have disappeared. A better understanding of anatomy and functional aspects of Patent Foramen Ovale (PFO) have slowly resulted in a more liberal approach toward the medical fitness to dive for those bearing a PFO. Circulating vascular gas emboli (VGE) are considered the key actors in ... -
Do Environmental Conditions Contribute to Narcosis Onset and Symptom Severity?
14 octobre 2016, HE Bruxelles BrabantArticle scientifiqueAlthough many factors contributing to inert gas narcosis onset and severity have been put forward, the available evidence is not particularly strong. Using objective criteria, we have assessed brain impairment associated with narcosis under various environmental diving conditions. 40 volunteers performed a no-decompression dive (33 m for 20 min) either in a dry chamber, a pool or open sea. They were ... -
Early detection of diving-related cognitive impairment of different nitrogen-oxygen gas mixtures
30 juin 2019, HE Bruxelles BrabantArticle scientifiqueNTRODUCTION: Cognitive impairment related to inert gas narcosis (IGN) is a threat to diving safety and operations at depth that might be reduced by using enriched air nitrox (EANx) mixtures. Using critical flicker fusion frequency (CFFF), a possible early detection of cognitive abilities/cerebral arousal impairment when breathing different oxygen (O2) fractions was investigated. METHODS: Eight male ... -
Early Endothelial Dysfunction in Type 1 Diabetes Is Accompanied by an Impairment of Vascular Smooth Muscle Function: A Meta-Analysis
05 mai 2020, HE Bruxelles BrabantArticle scientifiqueBackground: A large yet heterogeneous body of literature exists suggesting that endothelial dysfunction appears early in type 1 diabetes, due to hyperglycemia-induced oxidative stress. The latter may also affect vascular smooth muscles (VSM) function, a layer albeit less frequently considered in that pathology. This meta-analysis aims at evaluating the extent, and the contributing risk factors, of ... -
Editorial: Feelings of energy and fatigue: Two different moods
19 avril 2023, HE Bruxelles BrabantArticle scientifiqueEditorial on a special topic : Fatigue -
Editorial: Physiological telemonitoring and interventional telemedicine in extreme environments
22 janvier 2024, HE Bruxelles BrabantArticle scientifiqueEditorial on physiological measuring in extreme environments -
The effect of a passive stretch training protocol on performance during a drop jump in humans
30 mars 2013, HE Bruxelles BrabantArticle scientifiqueOur study's aim is to show how a five-week stretch training protocol, based on passive stretching, can change muscle performance during a drop jump (stretch shortening cycle). METHODS: This study observes in 8 healthy subjects (four males and four females), the effect of a 5-week passive stretch training protocol on the stretch shortening cycle (SSC) during the performance of a drop jump, and identify ... -
The effect of a passive stretch training protocol on performance during a drop jump in humans
15 juin 2013, HE Bruxelles BrabantArticle scientifiqueAim: Our study's aim is to show how a five-week stretch training protocol, based on passive stretching, can change muscle performance during a drop jump (stretch shortening cycle). Methods: This study observes in 8 healthy subjects (four males and four females), the effect of a 5-week passive stretch training protocol on the stretch shortening cycle (SSC) during the performance of a drop jump, ... -
Effect of a single, open-sea, air scuba dive on human micro- and macrovascular function
15 août 2013, HE Bruxelles BrabantArticle scientifiquePurpose: Previous studies have shown that bubble formation induced endothelial damage on conduit arteries. We aim to evaluate the effect of diving on microvascular and macrovascular function. Methods: Nine divers took part in a SCUBA dive at 30 msw (400 kPa), for 30 min of bottom time. Pre- and post-dive, they underwent an assessment of endothelial-dependent (acetylcholine) and endothelial-independent ... -
Effect of decompression-induced bubble formation on highly trained divers microvascular function
07 novembre 2013, HE Bruxelles BrabantArticle scientifiqueWe previously showed microvascular alteration of both endothelium-dependent and -independent reactivity after a single SCUBA dive. We aimed to study mechanisms involved in this postdive vascular dysfunction. Ten divers each completed three protocols: (1) a SCUBA dive at 400 kPa for 30 min; (2) a 41-min duration of seawater surface head immersed finning exercise to determine the effect of immersion ... -
Effect Of Induced Relative Hypoxia On Reticulocyte Count In Oncologycal Abdominal Surgery: A Single-Centre, Controlled, Randomized Pilot Study.
04 avril 2018, HE Bruxelles BrabantArticle scientifiqueErythropoietin (EPO) stimulating agents are known as alternatives to transfusion. However, they expose patients to thrombosis and are expensive. A phenomenon, “the normobaric oxygen paradox” (NOP), has been described. A transient hyperoxia followed by a prolonged return to normoxia acts as an effective trigger for EPO production. The mechanism depends on free O2 radicals and on reduced gluthatione ... -
Effect of oxygen-breathing during a decompression-stop on bubble-induced platelet activation after an open-sea air dive: oxygen-stop decompression
29 septembre 2013, HE Bruxelles BrabantArticle scientifiquePurpose: We highlighted a relationship between decompression-induced bubble formation and platelet micro-particle (PMP) release after a scuba air-dive. It is known that decompression protocol using oxygen-stop accelerates the washout of nitrogen loaded in tissues. The aim was to study the effect of oxygen deco-stop on bubble formation and cell-derived MP release. Methods: Healthy experienced ... -
The effect of pre-dive ingestion of dark chocolate on endothelial function after a scuba dive
15 mars 2015, HE Bruxelles BrabantArticle scientifiqueObjective: The aim of the study was to observe the effects of dark chocolate on endothelial function after scuba diving. Methods: Forty-two male scuba divers were divided into two groups: a control (n=21) and a chocolate group (n=21). They performed a 33-metres deep scuba-air dive for 20 minutes in a diving pool (Nemo 33, Brussels). Water temperature was 33⁰C. The chocolate group ingested 30 g ... -
Effect of SCUBA Diving on Ophthalmic Parameters
09 mars 2022, HE Bruxelles BrabantArticle scientifiqueBackground and Objective: Several cases of central serous chorioretinopathy (CSC) in divers have been reported in our medical retina center over the past few years. This study was designed to evaluate possible changes induced by SCUBA diving in ophthalmic parameters and especially subfoveal choroidal thickness (SFCT), since the choroid seems to play a crucial role in physiopathology of CSC. Materials ... -
Effect of simulated air dive and decompression sickness on the plasma proteome of rats
12 avril 2016, HE Bruxelles BrabantArticle scientifiquePurpose: Decompression sickness (DCS) is a poorly understood systemic disease caused by inadequate desaturation following a reduction in ambient pressure. Although recent studies highlight the importance of circulating factors, the available data are still puzzling. In this study, we aimed to identify proteins and biological pathways involved in the development of DCS in rats. Experimental design: ... -
Effect of splenectomy on platelet activation and decompression sickness outcome in a rat model of decompression
01 septembre 2014, HE Bruxelles BrabantArticle scientifiqueIntroduction: Splenic platelets have been recognized to have a greater prothrombotic potential than others platelets. We studied whether platelets released by splenic contraction could influence the severity and outcome of decompression sickness (DCS) and bubble-induced platelet activation. Methods: Sixteen, male Sprague-Dawley rats were randomly assigned to either a control or a splenectomized ... -
Effect of tetrahydrobiopterin and exercise training on endothelium-dependent vasorelaxation in SHR
02 juin 2013, HE Bruxelles BrabantArticle scientifiqueWe examined whether the improvement of impaired NO-dependent vasorelaxation by exercise training could be mediated through a BH4-dependent mechanism. Male spontaneously hypertensive rats (SHR, n = 20) and Wistar-Kyoto rats (WKY, n = 20) were trained (Tr) for 9 weeks on a treadmill and compared to age-matched sedentary animals (Sed). Endothelium-dependent vasorelaxation (EDV) was assessed with ... -
Effects of Acute Hypobaric Hypoxia Exposure on Cardiovascular Function in Unacclimatized Healthy Subjects: A "Rapid Ascent" Hypobaric Chamber Study
28 avril 2022, HE Bruxelles BrabantArticle scientifiqueBackground: This study aimed to observe the effects of a fast acute ascent to simulated high altitudes on cardiovascular function both in the main arteries and in peripheral circulation. Methods: We examined 17 healthy volunteers, between 18 and 50 years old, at sea level, at 3842 m of hypobaric hypoxia and after return to sea level. Cardiac output (CO) was measured with Doppler transthoracic ... -
Effects of Electrical Stimulation on Delayed Onset Muscle Soreness (DOMS): Evidences from Laboratory and In-Field Studies
12 septembre 2023, HE Bruxelles BrabantArticle scientifiqueIntense, long exercise can increase oxidative stress, leading to higher levels of inflammatory mediators and muscle damage. At the same time, fatigue has been suggested as one of the factors giving rise to delayed-onset muscle soreness (DOMS). The aim of this study was to investigate the efficacy of a specific electrical stimulation (ES) treatment (without elicited muscular contraction) on two ... -
Effects of oxygen-enriched air on cognitive performance during SCUBA-diving - an open-water study
12 avril 2017, HE Bruxelles BrabantArticle scientifiqueBackround: Nitrogen narcosis impairs cognitive function, a fact relevant during SCUBA-diving. Oxygen-enriched air (nitrox) became popular in recreational diving, while evidence of its advantages over air is limited. AIM: Compare effects of nitrox28 and air on two psychometric tests. METHODS: In this prospective, double-blind, open-water study, 108 advanced divers (38 females) were randomized to an ...