Parcourir HE2B - HE par auteur "Mrakic-Sposta, Simona"
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Effects of Electrical Stimulation on Delayed Onset Muscle Soreness (DOMS): Evidences from Laboratory and In-Field Studies
12 septembre 2023, Gussoni, Maristella; Moretti, Sarah; Vezzoli, Alessandra; Genitoni, Valerio; Giardini, Guido; BALESTRA, Costantino
; Bosco, Gerardo; Pratali, Lorenza; Spagnolo, Elisabetta; Montorsi, Michela; Mrakic-Sposta, Simona, HE Bruxelles Brabant
Article scientifiqueIntense, long exercise can increase oxidative stress, leading to higher levels of inflammatory mediators and muscle damage. At the same time, fatigue has been suggested as one of the factors giving rise to delayed-onset muscle soreness (DOMS). The aim of this study was to investigate the efficacy of a specific electrical stimulation (ES) treatment (without elicited muscular contraction) on two ... -
Full-Face Mask Use during SCUBA Diving Counters Related Oxidative Stress and Endothelial Dysfunction
15 janvier 2022, Levenez, Morgan; ; Mrakic-Sposta, Simona; Vezzoli, Alessandra; Germonpré, Peter; Pique, Hadrien; Virgili, Fabi; Bosco, Gerardo; Lafere, Pierre; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueImpaired flow mediated dilation (FMD), an index of vascular stress, is known after SCUBA diving. This is related to a dysfunction of nitric oxide (NO) availability and a disturbance of the redox status, possibly induced by hyperoxic/hyperbaric gas breathing. SCUBA diving is usually performed with a mask only covering "half face" (HF) and therefore forcing oral breathing. Nasal NO production is ... -
The Normobaric Oxygen Paradox-Hyperoxic Hypoxic Paradox: A Novel Expedient Strategy in Hematopoiesis Clinical Issues
janvier 2023, Salvagno, Michele; Coppalini, Giacomo; Taccone, Fabio-Silvio; Strapazzon, Giacomo; Mrakic-Sposta, Simona; Rocco, Monica; Khalife, Maher; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueHypoxia, even at non-lethal levels, is one of the most stressful events for all aerobic organisms as it significantly affects a wide spectrum of physiological functions and energy production. Aerobic organisms activate countless molecular responses directed to respond at cellular, tissue, organ, and whole-body levels to cope with oxygen shortage allowing survival, including enhanced neo-angiogenesis ... -
The "ON-OFF" Switching Response of Reactive Oxygen Species in Acute Normobaric Hypoxia: Preliminary Outcome
16 février 2023, BALESTRA, Costantino; Mrakic-Sposta, Simona; Gussoni, Maristella; Marzorati, Mauro; Porcelli, Simone; Bosco, Gerardo; Montorsi, Michela; Lafortuna, Claudio; Vezzoli, Alessandra, HE Bruxelles Brabant
Article scientifiqueExposure to acute normobaric hypoxia (NH) elicits reactive oxygen species (ROS) accumulation, whose production kinetics and oxidative damage were here investigated. Nine subjects were monitored while breathing an NH mixture (0.125 F(I)O(2) in air, about 4100 m) and during recovery with room air. ROS production was assessed by Electron Paramagnetic Resonance in capillary blood. Total antioxidant ... -
Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures
02 août 2023, Leveque, Clément; Mrakic-Sposta, Simona; ; Germonpré, Peter; ; Vezzoli, Alessandra; Bosco, Gerardo; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueHyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ... -
Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia Exposure
15 juin 2023, Leveque, Clément; Mrakic-Sposta, Simona; ; Germonpré, Peter; ; Vezzoli, Alessandra; Gussoni, Maristella; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueIn this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of 10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 females and 8 males, age: 32.2 ± 13.3 years old (mean ± SD), height: 169.1 ± 9.9 cm, and weight: 61.6 ± 16.2 kg) volunteered for the study. Blood samples were taken before, and at 30 min, 2 h, 8 h, 24 h, and 48 h after a 1 ... -
Oxidative Stress Response’s Kinetics after 60 Minutes at Different (30% or 100%) Normobaric Hyperoxia Exposures
30 décembre 2022, Leveque, Clément; Mrakic-Sposta, Simona; Lafère, Pierre; Vezzoli, Alessandra; Germonpré, Peter; Beer, Alexandre; Mievis, Stéphane; Virgili, Fabio; ; ; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueOxygen is a powerful trigger for cellular reactions and is used in many pathologies, including oxidative stress. However, the effects of oxygen over time and at different partial pressures remain poorly understood. In this study, the metabolic responses of normobaric oxygen intake for 1 h to mild (30%) and high (100%) inspired fractions were investigated. Fourteen healthy nonsmoking subjects (7 ... -
Oxygen Variations
26 septembre 2023, BALESTRA, Costantino; Virgili, Fabio; Mrakic-Sposta, Simona, HE Bruxelles Brabant
Livre/Ouvrage ou monographieFor many years, diving and hyperbaric medicine has strived to increase our understanding of the effects of environmental stressors on human pathophysiology. It has demonstrated the importance of oxygen and has taught us not to fear this oxidative molecule, the name of which is derived from the ancient Greek meaning the “acid generator” or Oxy-Gene; indeed, at that time, it was believed that all acids ... -
Oxygen Variations-Insights into Hypoxia, Hyperoxia and Hyperbaric Hyperoxia - Is the Dose the Clue?
20 septembre 2023, BALESTRA, Costantino; Mrakic-Sposta, Simona; Virgili, Fabio, HE Bruxelles Brabant
Article scientifiqueon, nitrogen and hydrogen); aerobic organisms depend on it to release energy from carbon-based molecules. The concentration of oxygen in the atmosphere is ~20.93–20.95% (209–460 ppm), but this has fluctuated markedly throughout geological history. It stabilized within a habitable range, between ~15% and 35%, which has been maintained from the Cambrian period 540 million years ago until today [1]. The ... -
Spirometry and oxidative stress after rebreather diving in warm water
05 août 2018, Bosco, Gerardo; Quartesan, Silvia; Mrakic-Sposta, Simona; Moretti, Sarah; BALESTRA, Costantino; Rubini, Alessandro, HE Bruxelles Brabant
Article scientifiqueIntroduction: Hyperbaric oxygen (HBO(2)) therapy and use of enriched air can result in oxidative injury affecting the brain, lungs and eyes. HBO(2) exposure during diving can lead to a decrease in respiratory parameters. However, the possible effects of acute exposure to oxygen-enriched diving on subsequent spirometric performance and oxidative state in humans have not been recently described recently. ...