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    • Construction of a Novel Chimeric Dextransucrase Fused to the Carbohydrate-Binding Module CBM2aPeer reviewedOpen access 

      28 septembre 2021, Fraga Vidal, Reinaldo; Ribalta, Roberto Carlos Arísticas; Dubreucq, Eric; Moreau, Benoît.; Martínez Valdès, Lisandra Teresa; Lafargue Gámez, Meinardo; Montes Alvarez, Amanda; Rubio Sánchez, Arianne, HE Condorcet
      Article scientifique
      Lactic acid bacteria (LAB) have the potential to produce homoexopolysaccharides (HoPS). Their health benefits and physicochemical properties have been the subject of extensive research. The HoPS functional properties are determined by molecular weight, the type of glycosidic link ages, degrees of branching and chemical composition. The dextransucrases (DSases) produce a kind of HoPS (dextrans), ...

    • Effects of Chemopreventive Natural Compounds on the Accuracy of 8-oxo-7,8-dihydro-2′-deoxyguanosine Translesion SynthesisPeer reviewedClosed access 

      08 juillet 2021, Nachtergael, Amandine; LANTERBECQ, Déborah; SPANOGHE, Martin; Belayew, Alexandra; Duez, Pierre, HE Condorcet
      Article scientifique
      Translesion synthesis is a DNA damage tolerance mechanism that relies on a series of specialized DNA polymerases able to bypass a lesion on a DNA template strand during replication or post-repair synthesis. Specialized translesion synthesis DNA polymerases pursue replication by inserting a base opposite to this lesion, correctly or incorrectly depending on the lesion nature, involved DNA polymerase(s), ...