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Scintigraphic Investigations of the Deep and Superficial Lymphatic Systems in the Evaluation of Lower Limb Oedema.

dc.rights.licenseCC1en_US
dc.contributor.authorBarbieux, romain
dc.contributor.authorLEDUC, Olivier
dc.contributor.authorBourgeois, Pierre
dc.contributor.authorRoman, Mirela
dc.contributor.authorDe backer, Pauline
dc.contributor.authorProvyn, Steven
dc.contributor.illustratorBarbieux, Romain
dc.date.accessioned2021-01-25T14:24:50Z
dc.date.available2021-01-25T14:24:50Z
dc.date.issued2019-09-23
dc.identifier.urihttps://luck.synhera.be/handle/123456789/572
dc.identifier.doidoi.org/10.1038/s41598-019-49554-7en_US
dc.description.abstractL'insuffisance lymphatique des membres inférieurs liée à un problème situé dans le compartiment intrafasciculaireen_US
dc.description.abstractenThe lymphoscintigraphic investigation (LySc) of the superficial lymphatic system (SLS) remains the gold standard for the diagnosis of lower limb lymphoedema. However, LySc of the deep lymphatic system (DLS) may be useful for diagnosing deep lymphatic system insufficiency in patients with lower limb oedema (LLE) but normal and/or paradoxical LySc of the SLS. The purpose of this study was therefore to evaluate a new LySc of the deep lymphatic system in patients presenting with a normal and/or paradoxical SLS exam showing LLE. In all, 15 patients with unilateral and 17 with bilateral LLE underwent 3-phased deep LySc of the lower limb via the injection of 99 mTc-labelled human serum albumin (HSA) nanocolloids in the Kager’s triangle. The absence of popliteal lymphatic node visualization after phase 2 of DLS LySc to diagnose a deep lymphatic insufficiency has a specificity and a sensitivity of 89% in patients with unilateral LLE and without associated venous symptoms. An insufficiency of the DLS was observed in 67% of cases with unilateral LLE and 59% of patients with bilateral LLE of venous and/or lymphatic origin. In conclusion, the lymphoscintigraphic visualization of the popliteal lymphatic nodes after the injection of 99 mTc-labelled HSA nanocolloids in the Kager’s triangle seems to be an effective way to diagnose DLS insufficiency in patients with LLE but normal findings in the SLS.en_US
dc.description.sponsorshipNoneen_US
dc.description.tableofcontentsAnalyse de lymphoscintigraphies bipédieuses superficielles et profondes de patients présentant une insuffisance de la circulation de retour des membres inférieurs.en_US
dc.language.isoENen_US
dc.publisherspringer natureen_US
dc.relation.ispartofScientific reports, Nature researchen_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/.en_US
dc.subject.enlymphatic drainageen_US
dc.titleScintigraphic Investigations of the Deep and Superficial Lymphatic Systems in the Evaluation of Lower Limb Oedema.en_US
dc.typeArticle scientifiqueen_US
synhera.classificationSciences de la santé humaineen_US
synhera.institutionHE Bruxelles Brabanten_US
synhera.stakeholders.fund0en_US
synhera.cost.total1500 eurosen_US
synhera.cost.apc1500 eurosen_US
synhera.cost.comp0en_US
synhera.cost.acccomp1500 eurosen_US
dc.description.versionOuien_US
dc.rights.holderles auteursen_US


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