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Soumissions récentes
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Effects of Electrical Stimulation on Delayed Onset Muscle Soreness (DOMS): Evidences from Laboratory and In-Field Studies
13 octobre 2023, Maristella Gussoni; Sarah Moretti; Alessandra Vezzoli; Valerio Genitoni; Guido Giardini; BALESTRA, Costantino
; Gerardo Bosco; Lorenza Pratali; Elisabetta Spagnolo; Michela Montorsi; Simona Mrakic-Sposta, HE Bruxelles Brabant
Article scientifiqueIntense, long exercise can increase oxidative stress, leading to higher levels of inflammatory mediators and muscle damage. At the same time, fatigue has been suggested as one of the factors giving rise to delayed-onset muscle soreness (DOMS). The aim of this study was to investigate the efficacy of a specific electrical stimulation (ES) treatment (without elicited muscular contraction) on two ... -
Oxygen Variations—Insights into Hypoxia, Hyperoxia and Hyperbaric Hyperoxia—Is the Dose the Clue?
Article scientifiqueMolecular oxygen (O2) is one of the four most important elements on Earth (alongside carbon, nitrogen and hydrogen); aerobic organisms depend on it to release energy from carbon-based molecules. The concentration of oxygen in the atmosphere is 20.93–20.95% (209–460 ppm), but this has fluctuated markedly throughout geological history. It stabilized within a habitable range, Between ~15% and 35%, ... -
Reactive Oxygen Species (ROS), Reactive Nitrogen Species (RNS), Antioxidants, and Cerebral Vascular Tone
09 janvier 2024, Michele SALVAGNO; Elda STERCHELE; Mario ZACCARELLI; Simona MRAKIC-SPOSTA; Ian James WELSBY; BALESTRA, Costantino; Fabio Silvio TACCONE, HE Bruxelles Brabant
Autrehe brain's unique characteristics make it exceptionally susceptible to oxidative stress, which arises from an imbalance between reactive oxygen species (ROS) production, reactive nitrogen species (RNS) production, and antioxidant defense mechanisms. This review explores the factors contributing to the brain's vascular tone's vulnerability in the presence of oxidative damage, which can be of clinical ... -
Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures
août 2023, Clément Leveque; Simona Mrakic-Sposta; Sigrid Theunissen; Peter Germonpre; Kate Lambrechts; Alessandra Vezzoli; GERARDO BOSCO; Morgan Lévénez; Pierre Lafère; François Guerrero; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueHyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ... -
Pulpal and periodontal temperature rise during KTP laser use as a root planing complement in vitro
2005, Nammour, S.; Rocca, J.-P.; Keiani, K.; BALESTRA, Costantino; Snoeck, T.; Powell, L.; Van Reck, J., HE Bruxelles Brabant
Article scientifiqueOBJECTIVE: The purpose of this study was to define the optimal irradiation conditions of a KTP laser during root planing treatment. METHODS: The surfaces of 60 single-root human teeth were scaled with conventional instruments before lasing. The pulpal temperature increase was measured by means of one thermocouple placed in the pulp chamber and a second one placed on the root surface at 1 mm from the ... -
Normobaric oxygen can enhance protein captation by the lymphatic system in healthy humans.
janvier 2004, BALESTRA, Costantino; ; ; Ezquer M; ; Leduc A; Willeput F; Marroni A; Cali Corleo R; Vann R, HE Bruxelles Brabant
Article scientifiquehas been advocated for a long time. Several beneficial effects of NBO have been demonstrated, one of which is the faster elimination of tissue nitrogen bubbles. During DCS occurrence, a cascade of intravascular reactions has been demonstrated. These inflammatory reactions occur within minutes of the onset of DCS, and involve the precipitation of proteins on the gas-bubble interface, causing a ... -
The fractal approach as a tool to understand asymptomatic brain hyperintense MRI signals
2004, BALESTRA, Costantino; Marroni, A.; Farkas, B.; Peetrons, P.; Vanderschueren, F.; Duboc, E.; ; , HE Bruxelles Brabant
Article scientifiqueThe prevalence of a Patent Foramen Ovale is described in merely 30% of the asymptomatic population. This patency has been shown to be an increasing risk factor for paradoxical cerebral embolization. Some desaturation or decompression situations in human activities such as scuba diving or altitude flight are prone to provoke embolisations. The association with the presence of a patent Foramen Ovale ... -
Evidence for increasing patency of the foramen ovale in divers
2005, ; Hastir, F.; Dendale, P.; Marroni, A.; Nguyen, A.-F.; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiquesing a standardized contrast-enhanced transesophageal echocardiographic technique, a group of divers was reexamined for the presence and size of patent foramen ovale (PFO) 7 years after their initial examinations. Unexpected but significant increases in the prevalence and size of PFO were found, suggesting a possible increasing risk for decompression sickness in these divers over time. -
A deep stop during decompression from 82 fsw (25 m) significantly reduces bubbles and fast tissue gas tensions.
janvier 2004, Marroni A; Bennett PB; Cronje FJ; Cali-Corleo R; ; Pieri M; Bonuccelli C; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiquen spite of many modifications to decompression algorithms, the incidence of decompression sickness (DCS) in scuba divers has changed very little. The success of stage, compared to linear ascents, is well described yet theoretical changes in decompression ratios have diminished the importance of fast tissue gas tensions as critical for bubble generation. The most serious signs and symptoms of DCS ... -
Erythropoietin production can be enhanced by normobaric oxygen breathing in healthy humans
2004, BALESTRA, Costantino; ; Poortmans, J.; Marroni, A.; Schiettecatte, J.; Collard, J.-F.; , HE Bruxelles Brabant
Article scientifiqueErythropoietin (EPO) induces red blood cell production by activating red bone marrow progenitor cells, and is used therapeutically in chronic anemia. It is also used as an unauthorized adjunct to increase the oxygen transport capacity in the blood of athletes. Renal tissue hypoxia is the only widely accepted trigger for EPO production (1-3), even if new oxygen-sensitive sites have been recently ... -
Scuba diving can induce stress of the temporomandibular joint leading to headache [1]
Article scientifiqueIn ordinary recreational scuba diving, many anatomical parts can be involved in disorders of cranial regions: ears and eyes are involved but also sinuses. Dental problems are generally involved in barotraumas because of bad dental fillings or other matters of interest to the general dental practitioner.1 Very few papers have looked at the articular and periarticular problems of the temporomandibular joint ... -
Patent foramen ovale and decompression sickness in sports divers.
Article scientifiquePatency of the foramen ovale (PFO) may be a cause of unexplained decompression sickness (DCS) in sports divers. To assess the relationship between PFO and DCS, a case-control study was undertaken in a population of Belgian sports divers. Thirty-seven divers who suffered from neurological DCS were compared with matched control divers who never had DCS. All divers were investigated with transesophageal ... -
Effects of fatigue on the stretch reflex in a human muscle
Article scientifiqueThe effects of fatigue on the electromyographic (EMG) reflex activities were compared during sustained voluntary contractions and contractions evoked by electrical stimulation (30 Hz) in the human first dorsal interosseus (FDI). Short latency (SL), medium latency (ML) and long latency (LL) reflex responses to a ramp-and-hold stretch of the muscle were recorded and analysed in 27 healthy subjects of ... -
Reflex regulation during sustained and intermittent submaximal contractions in humans
Article scientifiqueTo investigate whether the intensity and duration of a sustained contraction influences reflex regulation, we compared sustained fatiguing contractions at 25 % and 50 % of maximal voluntary contraction (MVC) force in the human abductor pollicis brevis (APB) muscle. Because the activation of motoneurones during fatigue may be reflexively controlled by the metabolic status of the muscle, we also ... -
Intrathoracic pressure changes after Valsalva strain and other maneuvers: Implications for divers with patent foramen ovale
Article scientifiqueScuba divers with patent foramen ovale (PFO) may be at risk for paradoxical nitrogen gas emboli when performing maneuvers that cause a rebound blood loading to the right atrium. We measured the rise and fall in intrathoracic pressure (ITP) during various maneuvers in 15 divers. The tests were standard isometric exercises (control), forceful coughing, knee bend (with and without respiration blocked), ... -
The Impact of Inotropes and Vasopressors on Cerebral Oxygenation in Patients with Traumatic Brain Injury and Subarachnoid Hemorrhage: A Narrative Review
24 janvier 2024, Michele Salvagno; Federico Geraldini; Giacomo Coppalini; Chiara Robba; Elisa Gouvea Bogossian; Filippo Annoni; Eva Vitali; Elda Diletta Sterchele; BALESTRA, Costantino; Fabio Silvio Taccone, HE Bruxelles Brabant
Article scientifiqueTraumatic brain injury (TBI) and subarachnoid hemorrhage (SAH) are critical neurological conditions that necessitate specialized care in the Intensive Care Unit (ICU). Managing cerebral perfusion pressure (CPP) and mean arterial pressure (MAP) is of primary importance in these patients. To maintain targeted MAP and CPP, vasopressors and/or inotropes are commonly used. However, their effects on ... -
Pulsed Hyperoxia Acts on Plasmatic Advanced Glycation End Products and Advanced Oxidation Protein Products and Modulates Mitochondrial Biogenesis in Human Peripheral Blood Mononuclear Cells: A Pilot Study on the “Normobaric Oxygen Paradox”
18 février 2024, BALESTRA, Costantino; Sara Baldelli; Fabio Virgili; Michele Salvagno; Simona Mrakic-Sposta; Deborah Fratantonio, HE Bruxelles Brabant
Article scientifiqueThe “normobaric oxygen paradox” (NOP) describes the response to the return to normoxia after a hyperoxic event, sensed by tissues as an oxygen shortage, up-regulating redox-sensitive tran- scription factors. We have previously characterized the time trend of oxygen-sensitive transcription factors in human PBMCs, in which the return to normoxia after 30% oxygen is sensed as a hypoxic trigger, ... -
Oxidative Stress and Cerebral Vascular Tone: The Role of Reactive Oxygen and Nitrogen Species
05 mars 2024, Michele Salvagno; Elda Diletta Sterchele; Mario Zaccarelli; Simona Mrakic-Sposta; Ian James Welsby; BALESTRA, Costantino; Fabio Silvio Taccone, HE Bruxelles Brabant
Article scientifiquehe brain's unique characteristics make it exceptionally susceptible to oxidative stress, which arises from an imbalance between reactive oxygen species (ROS) production, reactive nitrogen species (RNS) production, and antioxidant defense mechanisms. This review explores the factors contributing to the brain's vascular tone's vulnerability in the presence of oxidative damage, which can be of clinical ... -
Oxy-Inflammation in Humans during Underwater Activities
06 mars 2024, Alessandra Vezzoli; Simona Mrakic-Sposta; Andrea Brizzolari; BALESTRA, Costantino; Enrico Maria Camporesi; Gerardo Bosco, HE Bruxelles Brabant
Article scientifiqueUnderwater activities are characterized by an imbalance between reactive oxygen/nitrogen species (RONS) and antioxidant mechanisms, which can be associated with an inflammatory response, depending on O(2) availability. This review explores the oxidative stress mechanisms and related inflammation status (Oxy-Inflammation) in underwater activities such as breath-hold (BH) diving, Self-Contained ... -
Physiology of deep closed circuit rebreather mixed gas diving: vascular gas emboli and biological changes during a week-long liveaboard safari
01 mars 2024, BALESTRA, Costantino; Leveque Clément; Mrakic-Sposta Simona; Wauthy Pierre; ; Tillmans Frauke; Guerrero François; Lafere Pierre; Vezzoli Alessandra, HE Bruxelles Brabant
Article scientifiqueIntroduction: Diving decompression theory hypothesizes inflammatory processes as a source of micronuclei which could increase related risks. Therefore, we tested 10 healthy, male divers. They performed 6–8 dives with a maximum of two dives per day at depths ranging from 21 to 122 msw with CCR mixed gas diving. Methods: Post-dive VGE were counted by echocardiography. Saliva and urine samples ...
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