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Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up

dc.rights.licenseOTHen_US
dc.contributor.authorPapadopoulou, Virginie
dc.contributor.authorEvgenidis, Sotiris
dc.contributor.authorEckersley, Robert
dc.contributor.authorMesimeris, Thodoris
dc.contributor.authorBALESTRA, Costantino
dc.contributor.authorKostoglou, Margaritis
dc.contributor.authorTang, Meng-Xing
dc.contributor.authorKarapantsios, Thodoris
dc.date.accessioned2021-01-31T23:05:46Z
dc.date.available2021-01-31T23:05:46Z
dc.date.issued2015-04-04
dc.identifier.issn0927-7765en_US
dc.identifier.urihttps://luck.synhera.be/handle/123456789/612
dc.identifier.doi0.1016/j.colsurfb.2015.03.027en_US
dc.description.abstractVascular gas bubbles are routinely observed after scuba dives using ultrasound imaging, however the precise formation mechanism and site of these bubbles are still debated and growth from decompression in vivo has not been extensively studied, due in part to imaging difficulties. An experimental set-up was developed for optical recording of bubble growth and density on tissue surface area during hyperbaric decompression. Muscle and fat tissues (rabbits, ex vivo) were covered with nitrogen saturated distilled water and decompression experiments performed, from 3 to 0bar, at a rate of 1bar/min. Pictures were automatically acquired every 5s from the start of the decompression for 1h with a resolution of 1.75mum. A custom MatLab analysis code implementing a circular Hough transform was written and shown to be able to track bubble growth sequences including bubble center, radius, contact line and contact angles over time. Bubble density, nucleation threshold and detachment size, as well as coalescence behavior, were shown significantly different for muscle and fat tissues surfaces, whereas growth rates after a critical size were governed by diffusion as expected. Heterogeneous nucleation was observed from preferential sites on the tissue substrate, where the bubbles grow, detach and new bubbles form in turn. No new nucleation sites were observed after the first 10min post decompression start so bubble density did not vary after this point in the experiment. In addition, a competition for dissolved gas between adjacent multiple bubbles was demonstrated in increased delay times as well as slower growth rates for non-isolated bubbles.en_US
dc.description.sponsorshipNoneen_US
dc.language.isoENen_US
dc.publisherElsevieren_US
dc.relation.ispartofColloids Surf B Biointerfacesen_US
dc.relation.isreferencedbyhttp://www.sciencedirect.com/science/article/pii/S0927776515001617en_US
dc.rights.urihttps://s100.copyright.com/AppDispatchServlet#formTopen_US
dc.subjectDecompression sicknessen_US
dc.subjectDegassingen_US
dc.subjectDiving adverse effectsen_US
dc.subjectMicronucleien_US
dc.titleDecompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set upen_US
dc.typeArticle scientifiqueen_US
synhera.classificationSciences de la santé humaineen_US
synhera.institutionHE Bruxelles Brabanten_US
synhera.otherinstitutionDepartment of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greeceen_US
synhera.otherinstitutionImaging Sciences & Biomedical Engineering Division, King's College London, London, UKen_US
synhera.otherinstitutionHyperbaric Department, St. Paul General Hospital of Thessaloniki, Thessaloniki, Greece.en_US
synhera.otherinstitutionBioengineering, Imperial College London, London, UK.en_US
synhera.cost.total0en_US
synhera.cost.apc0en_US
synhera.cost.comp0en_US
synhera.cost.acccomp0en_US
dc.description.versionOuien_US
dc.rights.holderElsevieren_US


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