• Inert Gas Mild Pressure Action on Healthy Humans: The “IPA” StudyPeer reviewedOpen access 

      10 novembre 2024, Costantino Balestra; Clément Leveque; Simona Mrakic-Sposta; Mathias Coulon; Romain Tumbarello; Alessandra Vezzoli; Gerardo Bosco; Zuha Imtiyaz; Stephen R. Thom, HE Bruxelles Brabant
      Article scientifique
      The goal of this study was to evaluate inflammatory and oxidative stress responses in human subjects (9 females and 15 males) (age [29.6 +/- 11.5 years old (mean +/- SD)], height [172.0 +/- 10.05 cm], and weight [67.8 +/- 12.4 kg]) exposed to 1.45 ATA of helium (He) or nitrogen (N(2)) without concurrent hyperoxia. We hypothesized that elevated gas pressures would elicit an inflammatory response ...
    • Inert Gas Mild Pressure Action on Healthy Humans: The “IPA” StudyPeer reviewedOpen access 

      10 novembre 2024, Costantino Balestra; Clément Leveque; Simona Mrakic-Sposta; Mathias Coulon; Romain Tumbarello; Alessandra Vezzoli; Gerardo Bosco; Zuha Imtiyaz; Stephen R. Thom, HE Bruxelles Brabant
      Article scientifique
      The goal of this study was to evaluate inflammatory and oxidative stress responses in human subjects (9 females and 15 males) (age [29.6 +/- 11.5 years old (mean +/- SD)], height [172.0 +/- 10.05 cm], and weight [67.8 +/- 12.4 kg]) exposed to 1.45 ATA of helium (He) or nitrogen (N(2)) without concurrent hyperoxia. We hypothesized that elevated gas pressures would elicit an inflammatory response ...
    • Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia ExposuresPeer reviewedOpen access 

      août 2023, Clément Leveque; Simona Mrakic-Sposta; Sigrid Theunissen; Peter Germonpre; Kate Lambrechts; Alessandra Vezzoli; GERARDO BOSCO; Morgan Lévénez; Pierre Lafère; François Guerrero; BALESTRA, Costantinoorcid-id, HE Bruxelles Brabant
      Article scientifique
      Hyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ...