• Colonic Fermentation Promotes Decompression sickness in RatsPeer reviewedOpen access 

      08 février 2016, Demaistre, Sébastien; Vallée, Nicolas; Gempp, Emmanuel; LAMBRECHTS, Kate; Louge, Pierre; Duchamp, Claude; Blatteau, Jean-Eric, HE Bruxelles Brabant
      Article scientifique
      Massive bubble formation after diving can lead to decompression sickness (DCS). During dives with hydrogen as a diluent for oxygen, decreasing the body's H2 burden by inoculating hydrogen-metabolizing microbes into the gut reduces the risk of DCS. So we set out to investigate if colonic fermentation leading to endogenous hydrogen production promotes DCS in fasting rats. Four hours before an experimental ...
    • Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?Peer reviewedOpen access 

      11 juillet 2018, LAMBRECHTS, Kate; Demaistre, Sébastien; Blatteau, Jean-Eric; Risso, Jean-Jacques; Vallée, Nicolas, HE Bruxelles Brabant
      Article scientifique
      In its severest forms, decompression sickness (DCS) may extend systemically and/or induce severe neurological deficits, including paralysis or even death. It seems that the sterile and ischemic inflammatory phenomena are consecutive to the reaction of the bubbles with the organism and that the blood platelet activation plays a determinant role in the development of DCS. According to the hypotheses ...