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    • Elevations of Extracellular Vesicles and Inflammatory Biomarkers in Closed Circuit SCUBA DiversPeer reviewedOpen access 

      22 mars 2023, Arya, Awadhesh; BALESTRA, Costantinoorcid-id; Bhopale, Veena; Tominen, Laura; Raisanen-Sokolowski, Anne; Dugrenot, Emmanuel; Thom, Stephen, HE Bruxelles Brabant
      Article scientifique
      Blood-borne extracellular vesicles and inflammatory mediators were evaluated in divers using a closed circuit rebreathing apparatus and custom-mixed gases to diminish some diving risks. "Deep" divers (n = 8) dove once to mean (+/-SD) 102.5 +/- 1.2 m of sea water (msw) for 167.3 +/- 11.5 min. "Shallow" divers (n = 6) dove 3 times on day 1, and then repetitively over 7 days to 16.4 +/- 3.7 msw, for ...

    • Evidence of Heritable Determinants of Decompression Sickness in RatsPeer reviewedClosed access 

      22 juillet 2017, Lautridou, Jacky; Buzzacott, Peter; Belhomme, Marc; Dugrenot, Emmanuel; Lafère, Pierre; BALESTRA, Costantinoorcid-id; Guerrero, François, HE Bruxelles Brabant
      Article scientifique
      NTRODUCTION: Decompression sickness (DCS) is a complex and poorly understood systemic disease caused by inadequate desaturation following a decrease of ambient pressure. Strong variability between individuals is observed for DCS occurrence. This raises questions concerning factors that may be involved in the inter-individual variability of DCS occurrence. This study aimed to experimentally assess ...

    • Physiological characteristics associated with increased resistance to decompression sickness in male and female ratsPeer reviewedOpen access 

      23 juillet 2020, Lautridou, Jacky; Dugrenot, Emmanuel; Amérand, Aline; Guernec, Anthony; Pichavant-Rafini, Karine; Gouvanec, Christelle; Inizan, Manon; Albacete, Gaelle; Belhomme, Marc; Galinat, Hubert; Lafère, Pierre; BALESTRA, Costantinoorcid-id; Guerrero, François; Moisan, Chistine; Buzzacott, Peter, HE Bruxelles Brabant
      Article scientifique
      Decompression sickness (DCS) is a complex and poorly understood systemic disease with wide inter-individual resistance variability. We selectively bred rats with a 3-fold greater resistance to DCS than standard ones. To investigate possible physiological mechanisms underlying the resistance to DCS, including sex-related differences in these mechanisms, 15 males and 15 females resistant to DCS were ...

    • Pulmonary Effects of One Week of Repeated Recreational Closed-Circuit Rebreather Dives in Cold WaterPeer reviewedOpen access 

      28 décembre 2022, Gouin, Emmanuel; BALESTRA, Costantinoorcid-id; Orsat, Jeremy; Dugrenot, Emmanuel; L'Her, Erwan, HE Bruxelles Brabant
      Article scientifique
      Background and Objectives: The use of closed-circuit rebreathers (CCRs) in recreational diving is gaining interest. However, data regarding its physiological effects are still scarce. Immersion, cold water, hyperoxia, exercise or the equipment itself could challenge the cardiopulmonary system. The purpose of this study was to examine the impact of CCR diving on lung function and autonomous cardiac ...