Parcourir Santé par auteur 

Voici les éléments 1-2 de 2

    • Effect Of Induced Relative Hypoxia On Reticulocyte Count In Oncologycal Abdominal Surgery: A Single-Centre, Controlled, Randomized Pilot Study.Peer reviewedOpen access 

      04 avril 2018, Khalife, Maher; Wiams, Kathleen; Ben Aziz, M; BALESTRA, Costantino; Sosnowski, Maurice, HE Bruxelles Brabant
      Article scientifique
      Erythropoietin (EPO) stimulating agents are known as alternatives to transfusion. However, they expose patients to thrombosis and are expensive. A phenomenon, “the normobaric oxygen paradox” (NOP), has been described. A transient hyperoxia followed by a prolonged return to normoxia acts as an effective trigger for EPO production. The mechanism depends on free O2 radicals and on reduced gluthatione ...

    • The Normobaric Oxygen Paradox-Hyperoxic Hypoxic Paradox: A Novel Expedient Strategy in Hematopoiesis Clinical IssuesPeer reviewedOpen access 

      janvier 2023, Salvagno, Michele; Coppalini, Giacomo; Taccone, Fabio-Silvio; Strapazzon, Giacomo; Mrakic-Sposta, Simona; Rocco, Monica; Khalife, Maher; BALESTRA, Costantino, HE Bruxelles Brabant
      Article scientifique
      Hypoxia, even at non-lethal levels, is one of the most stressful events for all aerobic organisms as it significantly affects a wide spectrum of physiological functions and energy production. Aerobic organisms activate countless molecular responses directed to respond at cellular, tissue, organ, and whole-body levels to cope with oxygen shortage allowing survival, including enhanced neo-angiogenesis ...