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Effect of simulated air dive and decompression sickness on the plasma proteome of rats
12 avril 2016, Lautridou, Jacky; Pichereau, Vianney; Artigaud, Sébastien; Buzzacott, Peter; Wang, Qiong; Bernay, Benoit; Driad, Sabrina; Mazur, Aleksandra; LAMBRECHTS, Kate; Theron, Michaël; Guerrero, François, HE Bruxelles BrabantArticle scientifiquePurpose: Decompression sickness (DCS) is a poorly understood systemic disease caused by inadequate desaturation following a reduction in ambient pressure. Although recent studies highlight the importance of circulating factors, the available data are still puzzling. In this study, we aimed to identify proteins and biological pathways involved in the development of DCS in rats. Experimental design: ... -
Evidence of Heritable Determinants of Decompression Sickness in Rats
22 juillet 2017, Lautridou, Jacky; Buzzacott, Peter; Belhomme, Marc; Dugrenot, Emmanuel; Lafère, Pierre; BALESTRA, Costantino; Guerrero, François, HE Bruxelles BrabantArticle scientifiqueNTRODUCTION: Decompression sickness (DCS) is a complex and poorly understood systemic disease caused by inadequate desaturation following a decrease of ambient pressure. Strong variability between individuals is observed for DCS occurrence. This raises questions concerning factors that may be involved in the inter-individual variability of DCS occurrence. This study aimed to experimentally assess ... -
Hydration status during commercial saturation diving measured by bioimpedance and urine specific gravity
29 septembre 2022, Werke, Stian Lande; Landswerk, Halvor Dagsson; Lautridou, Jacky; Imbert, Jean-Pierre; BALESTRA, Costantino; Eftedal, Ingrid, HE Bruxelles BrabantArticle scientifiqueExcessive fluid loss triggered by hyperbaric pressure, water immersion and hot water suits causes saturation divers to be at risk of dehydration. Dehydration is associated with reductions in mental and physical performance, resulting in less effective work and an increased risk of work-related accidents. In this study we examined the hydration status of 11 male divers over 19 days of a commercial ... -
Physiological characteristics associated with increased resistance to decompression sickness in male and female rats
23 juillet 2020, Lautridou, Jacky; Dugrenot, Emmanuel; Amérand, Aline; Guernec, Anthony; Pichavant-Rafini, Karine; Gouvanec, Christelle; Inizan, Manon; Albacete, Gaelle; Belhomme, Marc; Galinat, Hubert; Lafère, Pierre; BALESTRA, Costantino; Guerrero, François; Moisan, Chistine; Buzzacott, Peter, HE Bruxelles BrabantArticle scientifiqueDecompression sickness (DCS) is a complex and poorly understood systemic disease with wide inter-individual resistance variability. We selectively bred rats with a 3-fold greater resistance to DCS than standard ones. To investigate possible physiological mechanisms underlying the resistance to DCS, including sex-related differences in these mechanisms, 15 males and 15 females resistant to DCS were ...