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Effect Of Induced Relative Hypoxia On Reticulocyte Count In Oncologycal Abdominal Surgery: A Single-Centre, Controlled, Randomized Pilot Study.
04 avril 2018, Khalife, Maher; Wiams, Kathleen; Ben Aziz, M; BALESTRA, Costantino; Sosnowski, Maurice, HE Bruxelles BrabantArticle scientifiqueErythropoietin (EPO) stimulating agents are known as alternatives to transfusion. However, they expose patients to thrombosis and are expensive. A phenomenon, “the normobaric oxygen paradox” (NOP), has been described. A transient hyperoxia followed by a prolonged return to normoxia acts as an effective trigger for EPO production. The mechanism depends on free O2 radicals and on reduced gluthatione ...