Santé: Recent submissions
Voici les éléments 61-80 de 131
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Effect of oxygen-breathing during a decompression-stop on bubble-induced platelet activation after an open-sea air dive: oxygen-stop decompression
29 septembre 2013, HE Bruxelles BrabantArticle scientifiquePurpose: We highlighted a relationship between decompression-induced bubble formation and platelet micro-particle (PMP) release after a scuba air-dive. It is known that decompression protocol using oxygen-stop accelerates the washout of nitrogen loaded in tissues. The aim was to study the effect of oxygen deco-stop on bubble formation and cell-derived MP release. Methods: Healthy experienced ... -
Effect of decompression-induced bubble formation on highly trained divers microvascular function
07 novembre 2013, HE Bruxelles BrabantArticle scientifiqueWe previously showed microvascular alteration of both endothelium-dependent and -independent reactivity after a single SCUBA dive. We aimed to study mechanisms involved in this postdive vascular dysfunction. Ten divers each completed three protocols: (1) a SCUBA dive at 400 kPa for 30 min; (2) a 41-min duration of seawater surface head immersed finning exercise to determine the effect of immersion ... -
Effect of splenectomy on platelet activation and decompression sickness outcome in a rat model of decompression
01 septembre 2014, HE Bruxelles BrabantArticle scientifiqueIntroduction: Splenic platelets have been recognized to have a greater prothrombotic potential than others platelets. We studied whether platelets released by splenic contraction could influence the severity and outcome of decompression sickness (DCS) and bubble-induced platelet activation. Methods: Sixteen, male Sprague-Dawley rats were randomly assigned to either a control or a splenectomized ... -
Mechanism of action of antiplatelet drugs on decompression sickness in rats: a protective effect of anti-GPIIbIIIa therapy
15 mai 2015, HE Bruxelles BrabantArticle scientifiqueLiterature highlights the involvement of disseminated thrombosis in the pathophysiology of decompression sickness (DCS). We examined the effect of several antithrombotic treatments targeting various pathways on DCS outcome: acetyl salicylate, prasugrel, abciximab, and enoxaparin. Rats were randomly assigned to six groups. Groups 1 and 2 were a control nondiving group (C; n = 10) and a control diving ... -
Flying after diving: should recommendations be reviewed? In-flight echocardiographic study in bubble-prone and bubble-resistant divers
13 mai 2015, Cialoni, Danilo; Pieri, Massimo; BALESTRA, Costantino
; Marroni, Alessandro, HE Bruxelles Brabant
Article scientifiqueINTRODUCTION: Inert gas accumulated after multiple recreational dives can generate tissue supersaturation and bubble formation when ambient pressure decreases. We hypothesized that this could happen even if divers respected the currently recommended 24-hour pre-flight surface interval (PFSI). METHODS: We performed transthoracic echocardiography (TTE) on a group of 56 healthy scuba divers (39 male, ... -
Cutis Marmorata skin decompression sickness is a manifestation of brainstem bubble embolization, not of local skin bubbles
10 avril 2015, Germonpré, Peter; BALESTRA, Costantino; Obeid, Georges; Chers, Dirk, HE Bruxelles Brabant
Article scientifique"Cutis Marmorata" skin symptoms after diving, most frequently in the form of an itching or painful cutaneous red-bluish discoloration are commonly regarded as a mild form of decompression sickness (DCS), and treated with oxygen inhalation without reverting to hyperbaric recompression treatment. It has been observed that the occurrence of Cutis Marmorata is frequently associated with the presence of ... -
Decompression induced bubble dynamics on ex vivo fat and muscle tissue surfaces with a new experimental set up
04 avril 2015, Papadopoulou, Virginie; Evgenidis, Sotiris; Eckersley, Robert; Mesimeris, Thodoris; BALESTRA, Costantino; Kostoglou, Margaritis; Tang, Meng-Xing; Karapantsios, Thodoris, HE Bruxelles Brabant
Article scientifiqueVascular gas bubbles are routinely observed after scuba dives using ultrasound imaging, however the precise formation mechanism and site of these bubbles are still debated and growth from decompression in vivo has not been extensively studied, due in part to imaging difficulties. An experimental set-up was developed for optical recording of bubble growth and density on tissue surface area during ... -
Qu'est-ce qui va changer? - Capitre dans Coeur et Plongée
Livre/Ouvrage ou monographieLe monde sous-marin est devenu accessible au plus grand nombre. Les méthodes de plongée se sont diversifiées, la population de plongeurs aussi... Mais la plongée demeure une activité à risques. Les pathologies cardiaques peuvent faire courir des dangers importants, non seulement au plongeur, mais aussi à tous ceux impliqués en cas d'assistance. Or, les données concernant les décès en plongée mettent ... -
Influence of decompression sickness on vasocontraction of isolated rat vessels
18 février 2015, HE Bruxelles BrabantArticle scientifiqueStudies conducted in divers indicate that endothelium function is impaired following a dive even without decompression sickness (DCS). Our previous experiment conducted on rat isolated vessels showed no differences in endothelium-dependent vasodilation after a simulated dive even in the presence of DCS, while contractile response to phenylephrine was progressively impaired with increased decompression ... -
Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the "spadin" Antidepressant
16 février 2016, HE Bruxelles BrabantArticle scientifiqueIn mice, disseminated coagulation, inflammation, and ischemia induce neurological damage that can lead to death. These symptoms result from circulating bubbles generated by a pathogenic decompression. Acute fluoxetine treatment or the presence of the TREK-1 potassium channel increases the survival rate when mice are subjected to an experimental dive/decompression protocol. This is a paradox because ... -
Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?
11 juillet 2018, HE Bruxelles BrabantArticle scientifiqueIn its severest forms, decompression sickness (DCS) may extend systemically and/or induce severe neurological deficits, including paralysis or even death. It seems that the sterile and ischemic inflammatory phenomena are consecutive to the reaction of the bubbles with the organism and that the blood platelet activation plays a determinant role in the development of DCS. According to the hypotheses ... -
Simulated air dives induce superoxide, nitric oxide, peroxynitrite, and Ca 2+ alterations in endothelial cells
03 avril 2019, HE Bruxelles BrabantArticle scientifiqueHuman diving is known to induce endothelial dysfunction. The aim of this study was to decipher the mechanism of ROS production during diving through the measure of mitochondrial calcium concentration, peroxynitrite, NO°, and superoxide towards better understanding of dive-induced endothelial dysfunction. Air diving simulation using bovine arterial endothelial cells (compression rate 101 kPa/min to ... -
Endothelial function may be enhanced in the cutaneous microcirculation after a single air dive
30 septembre 2020, HE Bruxelles BrabantArticle scientifiqueIntroduction: The effects of scuba diving on the vessel wall have been studied mainly at the level of large conduit arteries. Data regarding the microcirculation are scarce and indicate that these two vascular beds are affected differently by diving. Methods: We assessed the changes in cutaneous microcirculation before an air scuba dive, then 30 min and 24 h after surfacing. Endothelium-dependent ... -
Factors influencing the severity of long-term sequelae in fishermen-divers with neurological decompression sickness
31 mars 2020, HE Bruxelles BrabantArticle scientifiqueIntroduction: Numerous studies have been conducted to identify the factors influencing the short-term prognosis for neurological decompression sickness (DCS). However, the long-term sequelae are rarely assessed. The purpose of this study to investigate the factors likely to influence the long-term prognosis. Methods: Twenty-seven Vietnamese fishermen-divers who on average 9 (SD 6) years beforehand ... -
Effect of a single, open-sea, air scuba dive on human micro- and macrovascular function
15 août 2013, ; Pontier, Jean-Michel; BALESTRA, Costantino; Mazur, Aleksandra; Wang, Qiong; Buzzacott, Peter; Theron, Michaël; Mansourati, Jacques; Guerrero, François, HE Bruxelles Brabant
Article scientifiquePurpose: Previous studies have shown that bubble formation induced endothelial damage on conduit arteries. We aim to evaluate the effect of diving on microvascular and macrovascular function. Methods: Nine divers took part in a SCUBA dive at 30 msw (400 kPa), for 30 min of bottom time. Pre- and post-dive, they underwent an assessment of endothelial-dependent (acetylcholine) and endothelial-independent ... -
A ternary model of decompression sickness in rats
01 décembre 2014, Buzzacott, Peter; ; Mazur, Aleksandra; Wang, Qiong; Papadopoulou, Virginie; Theron, Michaël; BALESTRA, Costantino; Guerrero, François, HE Bruxelles Brabant
Article scientifiqueBackground: Decompression sickness (DCS) in rats is commonly modelled as a binary outcome. The present study aimed to develop a ternary model of predicting probability of DCS in rats, (as no-DCS, survivable-DCS or death), based upon the compression/decompression profile and physiological characteristics of each rat. Methods: A literature search identified dive profiles with outcomes no-DCS, ... -
Ultrasound lung "comets" increase after breath-hold diving
23 octobre 2010, ; ; Charbel, Brian; Cialoni, Danilo; Musimu, Patrick; Sponsiello, Nicola; Marroni, Alessandro; Pastouret, Fredéric; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueThe purpose of the study was to analyze the ultrasound lung comets (ULCs) variation, which are a sign of extra-vascular lung water. Forty-two healthy individuals performed breath-hold diving in different conditions: dynamic surface apnea; deep variable-weight apnea and shallow, face immersed without effort (static maximal and non-maximal). The number of ULCs was evaluated by means of an ultrasound ... -
Oxidative stress in breath-hold divers after repetitive dives
08 juin 2013, ; Sponciello, Nicholas; Rozloznik, Miroslav; ; Guerrero, François; Cialoni, Danilo; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueIntroduction: Hyperoxia causes oxidative stress. Breath-hold diving is associated with transient hyperoxia followed by hypoxia and a build-up of carbon dioxide (CO₂), chest-wall compression and significant haemodynamic changes. This study analyses variations in plasma oxidative stress markers after a series of repetitive breath-hold dives. Methods: Thirteen breath-hold divers were asked to perform ... -
The 'normobaric oxygen paradox': does it increase haemoglobin?
14 juin 2012, De Bels, David; ; Devriendt, Jacques; ; Lafère, Pierre; Valsamis, Joseph; ; Meeus, Philippe; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueBackground: A novel approach to increasing erythropoietin (EPO) using oxygen (O2) (the 'normobaric oxygen paradox') has been reported in healthy volunteers. We investigated whether the EPO increase is sufficient to induce erythropoiesis by comparing two protocols of O2 administration. Methods: We compared the effect of daily versus alternate days 100% O2, breathed for 30 minutes, on haemoglobin ... -
The effect of a passive stretch training protocol on performance during a drop jump in humans
15 juin 2013, Lévénez, Morgan; ; Bottero, Antoine; ; Bruyère, A; Tinlot, Arnaud; BALESTRA, Costantino; Provyn, Steven, HE Bruxelles Brabant
Article scientifiqueAim: Our study's aim is to show how a five-week stretch training protocol, based on passive stretching, can change muscle performance during a drop jump (stretch shortening cycle). Methods: This study observes in 8 healthy subjects (four males and four females), the effect of a 5-week passive stretch training protocol on the stretch shortening cycle (SSC) during the performance of a drop jump, ...