Santé: Recent submissions
Voici les éléments 61-80 de 124
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Qu'est-ce qui va changer? - Capitre dans Coeur et Plongée
10 août 2017, HE Bruxelles BrabantLivre/Ouvrage ou monographieLe monde sous-marin est devenu accessible au plus grand nombre. Les méthodes de plongée se sont diversifiées, la population de plongeurs aussi... Mais la plongée demeure une activité à risques. Les pathologies cardiaques peuvent faire courir des dangers importants, non seulement au plongeur, mais aussi à tous ceux impliqués en cas d'assistance. Or, les données concernant les décès en plongée mettent ... -
Influence of decompression sickness on vasocontraction of isolated rat vessels
18 février 2015, HE Bruxelles BrabantArticle scientifiqueStudies conducted in divers indicate that endothelium function is impaired following a dive even without decompression sickness (DCS). Our previous experiment conducted on rat isolated vessels showed no differences in endothelium-dependent vasodilation after a simulated dive even in the presence of DCS, while contractile response to phenylephrine was progressively impaired with increased decompression ... -
Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the "spadin" Antidepressant
16 février 2016, HE Bruxelles BrabantArticle scientifiqueIn mice, disseminated coagulation, inflammation, and ischemia induce neurological damage that can lead to death. These symptoms result from circulating bubbles generated by a pathogenic decompression. Acute fluoxetine treatment or the presence of the TREK-1 potassium channel increases the survival rate when mice are subjected to an experimental dive/decompression protocol. This is a paradox because ... -
Tirofiban, a Glycoprotein IIb/IIIa Antagonist, Has a Protective Effect on Decompression Sickness in Rats: Is the Crosstalk Between Platelet and Leukocytes Essential?
11 juillet 2018, HE Bruxelles BrabantArticle scientifiqueIn its severest forms, decompression sickness (DCS) may extend systemically and/or induce severe neurological deficits, including paralysis or even death. It seems that the sterile and ischemic inflammatory phenomena are consecutive to the reaction of the bubbles with the organism and that the blood platelet activation plays a determinant role in the development of DCS. According to the hypotheses ... -
Simulated air dives induce superoxide, nitric oxide, peroxynitrite, and Ca 2+ alterations in endothelial cells
03 avril 2019, HE Bruxelles BrabantArticle scientifiqueHuman diving is known to induce endothelial dysfunction. The aim of this study was to decipher the mechanism of ROS production during diving through the measure of mitochondrial calcium concentration, peroxynitrite, NO°, and superoxide towards better understanding of dive-induced endothelial dysfunction. Air diving simulation using bovine arterial endothelial cells (compression rate 101 kPa/min to ... -
Endothelial function may be enhanced in the cutaneous microcirculation after a single air dive
30 septembre 2020, HE Bruxelles BrabantArticle scientifiqueIntroduction: The effects of scuba diving on the vessel wall have been studied mainly at the level of large conduit arteries. Data regarding the microcirculation are scarce and indicate that these two vascular beds are affected differently by diving. Methods: We assessed the changes in cutaneous microcirculation before an air scuba dive, then 30 min and 24 h after surfacing. Endothelium-dependent ... -
Factors influencing the severity of long-term sequelae in fishermen-divers with neurological decompression sickness
31 mars 2020, HE Bruxelles BrabantArticle scientifiqueIntroduction: Numerous studies have been conducted to identify the factors influencing the short-term prognosis for neurological decompression sickness (DCS). However, the long-term sequelae are rarely assessed. The purpose of this study to investigate the factors likely to influence the long-term prognosis. Methods: Twenty-seven Vietnamese fishermen-divers who on average 9 (SD 6) years beforehand ... -
Effect of a single, open-sea, air scuba dive on human micro- and macrovascular function
15 août 2013, HE Bruxelles BrabantArticle scientifiquePurpose: Previous studies have shown that bubble formation induced endothelial damage on conduit arteries. We aim to evaluate the effect of diving on microvascular and macrovascular function. Methods: Nine divers took part in a SCUBA dive at 30 msw (400 kPa), for 30 min of bottom time. Pre- and post-dive, they underwent an assessment of endothelial-dependent (acetylcholine) and endothelial-independent ... -
A ternary model of decompression sickness in rats
01 décembre 2014, HE Bruxelles BrabantArticle scientifiqueBackground: Decompression sickness (DCS) in rats is commonly modelled as a binary outcome. The present study aimed to develop a ternary model of predicting probability of DCS in rats, (as no-DCS, survivable-DCS or death), based upon the compression/decompression profile and physiological characteristics of each rat. Methods: A literature search identified dive profiles with outcomes no-DCS, ... -
Ultrasound lung "comets" increase after breath-hold diving
23 octobre 2010, HE Bruxelles BrabantArticle scientifiqueThe purpose of the study was to analyze the ultrasound lung comets (ULCs) variation, which are a sign of extra-vascular lung water. Forty-two healthy individuals performed breath-hold diving in different conditions: dynamic surface apnea; deep variable-weight apnea and shallow, face immersed without effort (static maximal and non-maximal). The number of ULCs was evaluated by means of an ultrasound ... -
Oxidative stress in breath-hold divers after repetitive dives
08 juin 2013, HE Bruxelles BrabantArticle scientifiqueIntroduction: Hyperoxia causes oxidative stress. Breath-hold diving is associated with transient hyperoxia followed by hypoxia and a build-up of carbon dioxide (CO₂), chest-wall compression and significant haemodynamic changes. This study analyses variations in plasma oxidative stress markers after a series of repetitive breath-hold dives. Methods: Thirteen breath-hold divers were asked to perform ... -
The 'normobaric oxygen paradox': does it increase haemoglobin?
14 juin 2012, HE Bruxelles BrabantArticle scientifiqueBackground: A novel approach to increasing erythropoietin (EPO) using oxygen (O2) (the 'normobaric oxygen paradox') has been reported in healthy volunteers. We investigated whether the EPO increase is sufficient to induce erythropoiesis by comparing two protocols of O2 administration. Methods: We compared the effect of daily versus alternate days 100% O2, breathed for 30 minutes, on haemoglobin ... -
The effect of a passive stretch training protocol on performance during a drop jump in humans
15 juin 2013, HE Bruxelles BrabantArticle scientifiqueAim: Our study's aim is to show how a five-week stretch training protocol, based on passive stretching, can change muscle performance during a drop jump (stretch shortening cycle). Methods: This study observes in 8 healthy subjects (four males and four females), the effect of a 5-week passive stretch training protocol on the stretch shortening cycle (SSC) during the performance of a drop jump, ... -
Effect of tetrahydrobiopterin and exercise training on endothelium-dependent vasorelaxation in SHR
02 juin 2013, HE Bruxelles BrabantArticle scientifiqueWe examined whether the improvement of impaired NO-dependent vasorelaxation by exercise training could be mediated through a BH4-dependent mechanism. Male spontaneously hypertensive rats (SHR, n = 20) and Wistar-Kyoto rats (WKY, n = 20) were trained (Tr) for 9 weeks on a treadmill and compared to age-matched sedentary animals (Sed). Endothelium-dependent vasorelaxation (EDV) was assessed with ... -
A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving
07 novembre 2015, HE Bruxelles BrabantArticle scientifiqueNutritional antioxidants have been proposed as an expedient strategy to counter the potentially deleterious effects of scuba diving on endothelial function, flow-mediated dilation (FMD) and heart function. Sixteen volunteers performing a single standard dive (20 min at 33 m) according to US Navy diving procedures were randomly assigned to two groups: one was administered with two doses of 200 mg of ... -
Relationships between plasma lipids, proteins, surface tension and post-dive bubbles
13 février 2015, HE Bruxelles BrabantArticle scientifiqueDecompression sickness (DCS) in divers is caused by bubbles of inert gas. When DCS occurs, most bubbles can be found in the venous circulation: venous gas emboli (VGE). Bubbles are thought to be stabilized by low molecular weight surfactant reducing the plasma-air surface tension (γ). Proteins may play a role as well. We studied the interrelations between these substances, γ and VGE, measured before ... -
Diving deeper into SCUBA Science
12 février 2017, HE Bruxelles BrabantLivre/Ouvrage ou monographieThe editors of and authors of this book are a cadre of scientists and physicians with broad experience and knowledge of diving physiology and decompression theory. As is often the case, it requires a group effort to succeed in advancing practical knowledge. The colloquialism "the whole is greater than the sum of its parts" is often true and the PHYPODE Reasearch Group epitomizes this concept. By ... -
Do Environmental Conditions Contribute to Narcosis Onset and Symptom Severity?
14 octobre 2016, HE Bruxelles BrabantArticle scientifiqueAlthough many factors contributing to inert gas narcosis onset and severity have been put forward, the available evidence is not particularly strong. Using objective criteria, we have assessed brain impairment associated with narcosis under various environmental diving conditions. 40 volunteers performed a no-decompression dive (33 m for 20 min) either in a dry chamber, a pool or open sea. They were ... -
Effects of oxygen-enriched air on cognitive performance during SCUBA-diving - an open-water study
12 avril 2017, HE Bruxelles BrabantArticle scientifiqueBackround: Nitrogen narcosis impairs cognitive function, a fact relevant during SCUBA-diving. Oxygen-enriched air (nitrox) became popular in recreational diving, while evidence of its advantages over air is limited. AIM: Compare effects of nitrox28 and air on two psychometric tests. METHODS: In this prospective, double-blind, open-water study, 108 advanced divers (38 females) were randomized to an ... -
Evidence of Heritable Determinants of Decompression Sickness in Rats
22 juillet 2017, HE Bruxelles BrabantArticle scientifiqueNTRODUCTION: Decompression sickness (DCS) is a complex and poorly understood systemic disease caused by inadequate desaturation following a decrease of ambient pressure. Strong variability between individuals is observed for DCS occurrence. This raises questions concerning factors that may be involved in the inter-individual variability of DCS occurrence. This study aimed to experimentally assess ...