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Influence of decompression sickness on vasocontraction of isolated rat vessels
18 février 2015,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Studies conducted in divers indicate that endothelium function is impaired following a dive even without decompression sickness (DCS). Our previous experiment conducted on rat isolated vessels showed no differences in endothelium-dependent vasodilation after a simulated dive even in the presence of DCS, while contractile response to phenylephrine was progressively impaired with increased decompression ...
Simulated air dives induce superoxide, nitric oxide, peroxynitrite, and Ca 2+ alterations in endothelial cells
03 avril 2019,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Human diving is known to induce endothelial dysfunction. The aim of this study was to decipher the mechanism of ROS production during diving through the measure of mitochondrial calcium concentration, peroxynitrite, NO°, and superoxide towards better understanding of dive-induced endothelial dysfunction. Air diving simulation using bovine arterial endothelial cells (compression rate 101 kPa/min to ...
Endothelial function may be enhanced in the cutaneous microcirculation after a single air dive
30 septembre 2020,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: The effects of scuba diving on the vessel wall have been studied mainly at the level of large conduit arteries. Data regarding the microcirculation are scarce and indicate that these two vascular beds are affected differently by diving.
Methods: We assessed the changes in cutaneous microcirculation before an air scuba dive, then 30 min and 24 h after surfacing. Endothelium-dependent ...
Effect of a single, open-sea, air scuba dive on human micro- and macrovascular function
15 août 2013,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Purpose: Previous studies have shown that bubble formation induced endothelial damage on conduit arteries. We aim to evaluate the effect of diving on microvascular and macrovascular function.
Methods: Nine divers took part in a SCUBA dive at 30 msw (400 kPa), for 30 min of bottom time. Pre- and post-dive, they underwent an assessment of endothelial-dependent (acetylcholine) and endothelial-independent ...
A ternary model of decompression sickness in rats
01 décembre 2014,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Background: Decompression sickness (DCS) in rats is commonly modelled as a binary outcome. The present study aimed to develop a ternary model of predicting probability of DCS in rats, (as no-DCS, survivable-DCS or death), based upon the compression/decompression profile and physiological characteristics of each rat.
Methods: A literature search identified dive profiles with outcomes no-DCS, ...
Oxidative stress in breath-hold divers after repetitive dives
08 juin 2013,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Introduction: Hyperoxia causes oxidative stress. Breath-hold diving is associated with transient hyperoxia followed by hypoxia and a build-up of carbon dioxide (CO₂), chest-wall compression and significant haemodynamic changes. This study analyses variations in plasma oxidative stress markers after a series of repetitive breath-hold dives.
Methods: Thirteen breath-hold divers were asked to perform ...
Effect of tetrahydrobiopterin and exercise training on endothelium-dependent vasorelaxation in SHR
02 juin 2013,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
We examined whether the improvement of impaired NO-dependent vasorelaxation by exercise training could be mediated through a BH4-dependent mechanism. Male spontaneously hypertensive rats (SHR, n = 20) and Wistar-Kyoto rats (WKY, n = 20) were trained (Tr) for 9 weeks on a treadmill and compared to age-matched sedentary animals (Sed). Endothelium-dependent vasorelaxation (EDV) was assessed with ...
Do Environmental Conditions Contribute to Narcosis Onset and Symptom Severity?
14 octobre 2016,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Although many factors contributing to inert gas narcosis onset and severity have been put forward, the available evidence is not particularly strong. Using objective criteria, we have assessed brain impairment associated with narcosis under various environmental diving conditions. 40 volunteers performed a no-decompression dive (33 m for 20 min) either in a dry chamber, a pool or open sea. They were ...
Evidence of Heritable Determinants of Decompression Sickness in Rats
22 juillet 2017,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
NTRODUCTION: Decompression sickness (DCS) is a complex and poorly understood systemic disease caused by inadequate desaturation following a decrease of ambient pressure. Strong variability between individuals is observed for DCS occurrence. This raises questions concerning factors that may be involved in the inter-individual variability of DCS occurrence. This study aimed to experimentally assess ...
Extreme Environments in Movement Science and Sport Psychology
20 décembre 2018,
- HE Bruxelles Brabant
,
- Article scientifique
Article scientifique
Editorial: Extreme Environments in Movement Science and Sport Psychology