Santé: Recent submissions
Voici les éléments 21-40 de 124
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Effects of Acute Hypobaric Hypoxia Exposure on Cardiovascular Function in Unacclimatized Healthy Subjects: A "Rapid Ascent" Hypobaric Chamber Study
28 avril 2022, ; BALESTRA, Costantino
; Bolognési, Sébastien; Borgers, Guy; Vissenaeken, Dirk; Obeid, Georges; Germonpré, Peter; Honoré, Patrick M.; De Bels, David, HE Bruxelles Brabant
Article scientifiqueBackground: This study aimed to observe the effects of a fast acute ascent to simulated high altitudes on cardiovascular function both in the main arteries and in peripheral circulation. Methods: We examined 17 healthy volunteers, between 18 and 50 years old, at sea level, at 3842 m of hypobaric hypoxia and after return to sea level. Cardiac output (CO) was measured with Doppler transthoracic ... -
Oxidative Stress Response Kinetics after 60 Minutes at Different Levels (10% or 15%) of Normobaric Hypoxia Exposure
15 juin 2023, Leveque, Clément; Mrakic-Sposta, Simona; ; Germonpré, Peter; ; Vezzoli, Alessandra; Gussoni, Maristella; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueIn this study, the metabolic responses of hypoxic breathing for 1 h to inspired fractions of 10% and 15% oxygen were investigated. To this end, 14 healthy nonsmoking subjects (6 females and 8 males, age: 32.2 ± 13.3 years old (mean ± SD), height: 169.1 ± 9.9 cm, and weight: 61.6 ± 16.2 kg) volunteered for the study. Blood samples were taken before, and at 30 min, 2 h, 8 h, 24 h, and 48 h after a 1 ... -
Effects of Electrical Stimulation on Delayed Onset Muscle Soreness (DOMS): Evidences from Laboratory and In-Field Studies
12 septembre 2023, Gussoni, Maristella; Moretti, Sarah; Vezzoli, Alessandra; Genitoni, Valerio; Giardini, Guido; BALESTRA, Costantino; Bosco, Gerardo; Pratali, Lorenza; Spagnolo, Elisabetta; Montorsi, Michela; Mrakic-Sposta, Simona, HE Bruxelles Brabant
Article scientifiqueIntense, long exercise can increase oxidative stress, leading to higher levels of inflammatory mediators and muscle damage. At the same time, fatigue has been suggested as one of the factors giving rise to delayed-onset muscle soreness (DOMS). The aim of this study was to investigate the efficacy of a specific electrical stimulation (ES) treatment (without elicited muscular contraction) on two ... -
Oxygen Variations
26 septembre 2023, BALESTRA, Costantino; Virgili, Fabio; Mrakic-Sposta, Simona, HE Bruxelles Brabant
Livre/Ouvrage ou monographieFor many years, diving and hyperbaric medicine has strived to increase our understanding of the effects of environmental stressors on human pathophysiology. It has demonstrated the importance of oxygen and has taught us not to fear this oxidative molecule, the name of which is derived from the ancient Greek meaning the “acid generator” or Oxy-Gene; indeed, at that time, it was believed that all acids ... -
Hyperbaric medicine
Livre/Ouvrage ou monographieOxygen (both its presence and absence) acts as a potent signaling mechanism in many, if not most, cellular processes. Oxygen has been used therapeutically mainly to alleviate or correct hypoxia, and has been administered in supra-atmospheric doses in the form of hyperbaric oxygen (a method derived from diving medicine practices, but has been used in non-diving applications since the 1960s). Hyperbaric ... -
Oxidative Stress Response Kinetics after 60 Minutes at Different (1.4 ATA and 2.5 ATA) Hyperbaric Hyperoxia Exposures
02 août 2023, Leveque, Clément; Mrakic-Sposta, Simona; ; Germonpré, Peter; ; Vezzoli, Alessandra; Bosco, Gerardo; Levenez, Morgan; Lafère, Pierre; Guerrero, François; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueHyperbaric oxygen therapy (HBOT) is a therapeutical approach based on exposure to pure oxygen in an augmented atmospheric pressure. Although it has been used for years, the exact kinetics of the reactive oxygen species (ROS) between different pressures of hyperbaric oxygen exposure are still not clearly evidenced. In this study, the metabolic responses of hyperbaric hyperoxia exposures for 1 h at ... -
Varying Oxygen Partial Pressure Elicits Blood-Borne Microparticles Expressing Different Cell-Specific Proteins-Toward a Targeted Use of Oxygen?
17 juillet 2022, BALESTRA, Costantino; Arya, Awadhesh; Leveque, Clément; Virgili, Fabio; ; ; Lafere, Pierre; Thom, Stephen, HE Bruxelles Brabant
Article scientifiqueOxygen is a powerful trigger for cellular reactions, but there are few comparative investigations assessing the effects over a large range of partial pressures. We investigated a metabolic response to single exposures to either normobaric (10%, 15%, 30%, 100%) or hyperbaric (1.4 ATA, 2.5 ATA) oxygen. Forty-eight healthy subjects (32 males/16 females; age: 43.7 +/- 13.4 years, height: 172.7 +/- 10.07 ... -
Effect of SCUBA Diving on Ophthalmic Parameters
09 mars 2022, Deleu, Laurent; Catherine, Janet; Postelmans, Laurence; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueBackground and Objective: Several cases of central serous chorioretinopathy (CSC) in divers have been reported in our medical retina center over the past few years. This study was designed to evaluate possible changes induced by SCUBA diving in ophthalmic parameters and especially subfoveal choroidal thickness (SFCT), since the choroid seems to play a crucial role in physiopathology of CSC. Materials ... -
Vascular Function Recovery Following Saturation Diving
Article scientifiqueBackground and Objectives: Saturation diving is a technique used in commercial diving. Decompression sickness (DCS) was the main concern of saturation safety, but procedures have evolved over the last 50 years and DCS has become a rare event. New needs have evolved to evaluate the diving and decompression stress to improve the flexibility of the operations (minimum interval between dives, optimal ... -
Full-Face Mask Use during SCUBA Diving Counters Related Oxidative Stress and Endothelial Dysfunction
15 janvier 2022, Levenez, Morgan; ; Mrakic-Sposta, Simona; Vezzoli, Alessandra; Germonpré, Peter; Pique, Hadrien; Virgili, Fabi; Bosco, Gerardo; Lafere, Pierre; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueImpaired flow mediated dilation (FMD), an index of vascular stress, is known after SCUBA diving. This is related to a dysfunction of nitric oxide (NO) availability and a disturbance of the redox status, possibly induced by hyperoxic/hyperbaric gas breathing. SCUBA diving is usually performed with a mask only covering "half face" (HF) and therefore forcing oral breathing. Nasal NO production is ... -
The Normobaric Oxygen Paradox-Hyperoxic Hypoxic Paradox: A Novel Expedient Strategy in Hematopoiesis Clinical Issues
janvier 2023, Salvagno, Michele; Coppalini, Giacomo; Taccone, Fabio-Silvio; Strapazzon, Giacomo; Mrakic-Sposta, Simona; Rocco, Monica; Khalife, Maher; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueHypoxia, even at non-lethal levels, is one of the most stressful events for all aerobic organisms as it significantly affects a wide spectrum of physiological functions and energy production. Aerobic organisms activate countless molecular responses directed to respond at cellular, tissue, organ, and whole-body levels to cope with oxygen shortage allowing survival, including enhanced neo-angiogenesis ... -
Hydration status during commercial saturation diving measured by bioimpedance and urine specific gravity
29 septembre 2022, Werke, Stian Lande; Landswerk, Halvor Dagsson; Lautridou, Jacky; Imbert, Jean-Pierre; BALESTRA, Costantino; Eftedal, Ingrid, HE Bruxelles Brabant
Article scientifiqueExcessive fluid loss triggered by hyperbaric pressure, water immersion and hot water suits causes saturation divers to be at risk of dehydration. Dehydration is associated with reductions in mental and physical performance, resulting in less effective work and an increased risk of work-related accidents. In this study we examined the hydration status of 11 male divers over 19 days of a commercial ... -
Mini Trampoline, a New and Promising Way of SCUBA Diving Preconditioning to Reduce Vascular Gas Emboli?
29 avril 2022, ; ; Vandenheede, Joaquim; Delorme, Manon; Lafere, Pierre; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueBackground: Despite evolution in decompression algorithms, decompression illness is still an issue nowadays. Reducing vascular gas emboli (VGE) production or preserving endothelial function by other means such as diving preconditioning is of great interest. Several methods have been tried, either mechanical, cardiovascular, desaturation aimed or biochemical, with encouraging results. In this study, ... -
Elevations of Extracellular Vesicles and Inflammatory Biomarkers in Closed Circuit SCUBA Divers
22 mars 2023, Arya, Awadhesh; BALESTRA, Costantino; Bhopale, Veena; Tominen, Laura; Raisanen-Sokolowski, Anne; Dugrenot, Emmanuel; Thom, Stephen, HE Bruxelles Brabant
Article scientifiqueBlood-borne extracellular vesicles and inflammatory mediators were evaluated in divers using a closed circuit rebreathing apparatus and custom-mixed gases to diminish some diving risks. "Deep" divers (n = 8) dove once to mean (+/-SD) 102.5 +/- 1.2 m of sea water (msw) for 167.3 +/- 11.5 min. "Shallow" divers (n = 6) dove 3 times on day 1, and then repetitively over 7 days to 16.4 +/- 3.7 msw, for ... -
Editorial: Feelings of energy and fatigue: Two different moods
19 avril 2023, Boolani, Ali; Martin, Joel; D'acquisto, Fulvio; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueEditorial on a special topic : Fatigue -
Pulmonary Effects of One Week of Repeated Recreational Closed-Circuit Rebreather Dives in Cold Water
28 décembre 2022, Gouin, Emmanuel; BALESTRA, Costantino; Orsat, Jeremy; Dugrenot, Emmanuel; L'Her, Erwan, HE Bruxelles Brabant
Article scientifiqueBackground and Objectives: The use of closed-circuit rebreathers (CCRs) in recreational diving is gaining interest. However, data regarding its physiological effects are still scarce. Immersion, cold water, hyperoxia, exercise or the equipment itself could challenge the cardiopulmonary system. The purpose of this study was to examine the impact of CCR diving on lung function and autonomous cardiac ... -
Architectural and Mechanical Changes after Five Weeks of Intermittent Static Stretch Training on the Medial Gastrocnemius Muscle of Active Adults
27 mars 2023, Levenez, Morgan; Moeremans, Mathieu; Boorghs, Cédric; Vigouroux, Florent; Leveque, Clément; ; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueWe investigated the effects of intermittent long-term stretch training (5 weeks) on the architectural and mechanical properties of the muscle-tendon unit (MTU) in healthy humans. MTU's viscoelastic and architectural properties in the human medial gastrocnemius (MG) muscle and the contribution of muscle and tendon structures to the MTU lengthening were analyzed. Ten healthy volunteers participated ... -
Oxygen Variations-Insights into Hypoxia, Hyperoxia and Hyperbaric Hyperoxia - Is the Dose the Clue?
20 septembre 2023, BALESTRA, Costantino; Mrakic-Sposta, Simona; Virgili, Fabio, HE Bruxelles Brabant
Article scientifiqueon, nitrogen and hydrogen); aerobic organisms depend on it to release energy from carbon-based molecules. The concentration of oxygen in the atmosphere is ~20.93–20.95% (209–460 ppm), but this has fluctuated markedly throughout geological history. It stabilized within a habitable range, between ~15% and 35%, which has been maintained from the Cambrian period 540 million years ago until today [1]. The ... -
Heart Rate Variability During a Standard Dive: A Role for Inspired Oxygen Pressure?
13 août 2021, Lafère, Pierre; ; ; Balestra, Ambre; Germonpré, Faye-Lisa; Marroni, Alessandro; Cialoni, Danilo; Bosco, Gerardo; BALESTRA, Costantino, HE Bruxelles Brabant
Article scientifiqueIntroduction: Heart rate variability (HRV) during underwater diving has been infrequently investigated because of environment limitations and technical challenges. This study aims to analyze HRV changes while diving at variable hyperoxia when using open circuit (OC) air diving apparatus or at constant hyperoxia using a closed-circuit rebreather (CCR). We used HRV analysis in time and frequency domain ... -
Comparison of insulation provided by dry or wetsuits among recreational divers during cold water immersion (< 5 degrees C)
Article scientifiqueBACKGROUND: Divers thermal status influences susceptibility to decompression sickness hence the need for proper insulation during immersion in cold water. However, there is a lack of data on thermal protection provided by diving suits, hence this study. MATERIALS AND METHODS: Two different groups of divers wearing either a wetsuit (n = 15) or a dry suit (n = 15) volunteered for this study. Anthropometric ...